...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Proton dosimetry intercomparison based on the ICRU report 59 protocol.
【24h】

Proton dosimetry intercomparison based on the ICRU report 59 protocol.

机译：基于ICRU报告59协议的质子剂量比对。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND AND PURPOSE: A new protocol for calibration of proton beams was established by the ICRU in report 59 on proton dosimetry. In this paper we report the results of an international proton dosimetry intercomparison, which was held at Loma Linda University Medical Center. The goals of the intercomparison were, first, to estimate the level of consistency in absorbed dose delivered to patients if proton beams at various clinics were calibrated with the new ICRU protocol, and second, to evaluate the differences in absorbed dose determination due to differences in 60Co-based ionization chamber calibration factors. MATERIALS AND METHODS: Eleven institutions participated in the intercomparison. Measurements were performed in a polystyrene phantom at a depth of 10.27 cm water equivalent thickness in a 6-cm modulated proton beam with an accelerator energy of 155 MeV and an incident energy of approximately 135 MeV. Most participants used ionization chambers calibrated in terms of exposure or air kerma. Four ionization chambers had 60Co-based calibration in terms of absorbed dose-to-water. Two chambers were calibrated in a 60Co beam at the NIST both in terms of air kerma and absorbed dose-to-water to provide a comparison of ionization chambers with different calibrations. RESULTS: The intercomparison showed that use of the ICRU report 59 protocol would result in absorbed doses being delivered to patients at their participating institutions to within +/-0.9% (one standard deviation). The maximum difference between doses determined by the participants was found to be 2.9%. Differences between proton doses derived from the measurements with ionization chambers with N(K)-, or N(W) - calibration type depended on chamber type. CONCLUSIONS: Using ionization chambers with 60Co calibration factors traceable to standard laboratories and the ICRU report 59 protocol, a distribution of stated proton absorbed dose is achieved with a difference less than 3%. The ICRU protocol should be adopted for clinical proton beam calibration. A comparison of proton doses derived from measurements with different chambers indicates that the difference in results cannot be explained only by differences in 60Co calibration factors.
机译：背景与目的：ICRU在有关质子剂量的第59号报告中建立了用于质子束校准的新协议。在本文中，我们报告了在洛马琳达大学医学中心举行的国际质子剂量比对的结果。相互比较的目标是，首先，如果使用新的ICRU协议校准了各个诊所的质子束，则估计了输送给患者的吸收剂量的一致性水平;其次，是评估了由于基于60Co的电离室校准因子。材料与方法：11个机构参加了比对。在6厘米调制质子束中以10.27厘米水当量厚度的深度在聚苯乙烯幻象中进行测量，加速器能量为155 MeV，入射能量为135 MeV。大多数参与者使用了根据暴露或空气比释动能校准的电离室。四个电离室的吸收剂量对水进行了基于60Co的校准。就空气比释动能和吸收的剂量/水而言，在NIST的60Co射线束中对两个反应室进行了校准，以比较不同校准条件下的电离室。结果：比较结果表明，使用ICRU报告59方案会导致在其参与机构向患者提供的吸收剂量在+/- 0.9％之内（一个标准偏差）。参与者确定的剂量之间的最大差异为2.9％。由具有N（K）-或N（W）-校准类型的电离室进行测量得出的质子剂量之间的差异取决于室的类型。结论：使用具有可溯源至标准实验室和ICRU报告59规程的60Co校准因子的电离室，可获得规定的质子吸收剂量分布，其差异小于3％。临床质子束校准应采用ICRU协议。对不同腔室测量得出的质子剂量的比较表明，结果的差异不能仅通过60Co校准因子的差异来解释。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号