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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Long term results of non-surgical, exclusive strontium-/yttrium-90 beta-irradiation of pterygia.
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Long term results of non-surgical, exclusive strontium-/yttrium-90 beta-irradiation of pterygia.

机译:翼状gia肉的非手术,锶-/钇-90β-辐射的长期治疗结果。

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摘要

BACKGROUND AND PURPOSE: To evaluate long term results and to demonstrate safety and efficacy of non-surgical, exclusive strontium-/yttrium-90 beta irradiation of non-operated pterygia. PATIENTS AND METHODS: Between March 1977 and April 1999, 43 patients with 54 primary pterygia were treated with an exclusive strontium-/yttrium-90 beta-irradiation up to a total dose of 50Gy divided in four fractions with one week apart. All patients were referred from the same ophthalmologist. The average follow-up were 112(+/-88 months (range, 12-321 months), median 96 months. RESULTS: The patients were referred with early symptomatic manifestations of pterygia with a mean horizontal diameter of 1.6+/-0.7mm (range, 0.5-4.5mm), which shrank to a mean diameter of 0.9+/-0.6mm (range, 0-2.5mm) after irradiation (P<0.005). There was a reduction of size in every pterygium, none of the 54 pterygia developed a recurrent growth and there were no patient with any late side effect. Following the strontium-/yttrium-90 application the process came up with an obliteration of the vessels, which resulted in a grey, thin and avascular pannus. CONCLUSIONS: Strontium-/yttrium-90 beta-irradiation as an exclusive, non-surgical treatment for early pterygia provides a significant reduction of the size of the irradiated pterygia, is a safe and effective therapy to prevent a recurrence and can be performed without late side effects.
机译:背景与目的:评估长期结果并证明非手术性翼状ery肉的非手术,锶-/钇-90 beta独家手术的安全性和有效性。患者与方法:在1977年3月至1999年4月之间,对43例54例原发性翼状gia肉患者进行了独家锶-/钇90-β放射治疗,总剂量为50Gy,分为四部分,间隔一周。所有患者均由同一位眼科医生转诊。平均随访112(+/- 88个月,范围12-321个月),中位96个月。结果:患者转诊患有翼状gia肉的早期症状,平均水平直径为1.6 +/- 0.7mm。 (范围:0.5-4.5mm),照射后收缩至平均直径0.9 +/- 0.6mm(范围,0-2.5mm)(P <0.005)。 54例翼状developed肉出现复发性生长,没有患者出现任何晚期副作用,在应用锶/钇90后,血管闭塞,形成了灰色,稀薄和无血管的pan。 :锶-/钇90β射线照射作为早期翼状gia肉的专有,非手术治疗,可显着减小辐照性翼状size肉的大小,是一种安全有效的疗法,可防止复发,并且可以不进行后侧手术效果。

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