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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Radiotherapy planning for lung cancer: slow CTs allow the drawing of tighter margins.
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Radiotherapy planning for lung cancer: slow CTs allow the drawing of tighter margins.

机译：肺癌的放射治疗计划：缓慢的CT允许缩小边界。

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BACKGROUND AND PURPOSE: Evaluation of the use of planning CTs with slow revolution time (4s/slice; 'slow CTs') in the planning procedure of radiotherapy for lung cancer patients in comparison to commonly used 'fast' planning CTs; impact on margin assessment of planning target volume (PTV) design. PATIENTS AND METHODS: Eighteen lung cancer patients (six upper, lower lobe and central tumors, respectively) have been scanned each by three series of slow CTs and one fast CT (spiral CT). Patients have been freely breathing. The largest transversal tumor diameters in slow and fast CTs have been measured. Tumor edge positions have been determined for six spatial directions in all slices of the three slow CT series. RESULTS: Slow CTs show larger dimensions of the visible tumor than fast CTs. The median difference of the diameter for all tumors is 2mm (range 0-4mm). Slow CTs deliver constant depictions of lung tumors within a range of 1.6mm in all directions. This margin is considered to be sufficient to compensate for tumor movements by respiration and cardiovascular motions (internal margin). A margin of 7 mm added to the GTV of a single slow CT series to draw the PTV is proposed. CONCLUSIONS: Slow planning CTs show larger, but highly constant depictions of lung tumors in comparison to conventional fast CT scanning, yielding an integral delineation of almost all positions of the moving tumors. Thus the use of slow planning CTs enables the drawing of tighter margins in external beam treatment planning of lung cancer.
机译：背景与目的：与常用的“快速”计划CT相比，评估肺癌患者放疗计划过程中使用慢旋转时间（4s /切片;“慢CT”）的计划CT的使用;对规划目标量（PTV）设计的保证金评估的影响。患者和方法：18例肺癌患者（分别为6个上，下叶和中央肿瘤）已通过三组慢速CT和一台快速CT（螺旋CT）进行了扫描。患者一直自由呼吸。已测量了慢速和快速CT中最大的横向肿瘤直径。已经确定了三个慢速CT系列所有切片中六个空间方向的肿瘤边缘位置。结果：慢速CT显示的可见肿瘤比快速CT更大。所有肿瘤的直径中值差异为2mm（范围0-4mm）。缓慢的CT可以在所有方向上连续显示1.6mm范围内的肺部肿瘤。该余量被认为足以补偿由于呼吸和心血管运动引起的肿瘤运动（内部余量）。建议在单个慢速CT系列的GTV上增加7毫米的边距以绘制PTV。结论：与常规的快速CT扫描相比，慢速计划的CT显示出较大但高度恒定的肺部肿瘤描述，几乎可以描述运动肿瘤的所有位置。因此，使用缓慢计划的CT可以在肺癌的外部束治疗计划中画出更窄的边界。

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