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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Effective avoidance of a functional spect-perfused lung using intensity modulated radiotherapy (IMRT) for non-small cell lung cancer (NSCLC): an update of a planning study.
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Effective avoidance of a functional spect-perfused lung using intensity modulated radiotherapy (IMRT) for non-small cell lung cancer (NSCLC): an update of a planning study.

机译:使用调强放射疗法(IMRT)有效避免非小细胞肺癌(NSCLC)的功能性斑点灌注肺:一项规划研究的更新。

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摘要

IMRT and 3-dimensional conformal radiotherapy (3-DCRT) plans of 25 patients with non-small cell lung (NSCLC) were compared in terms of planning target volume (PTV) coverage and sparing of functional lung (FL) defined by a SPECT perfusion scan. IMRT resulted in significant reduction of functional V(20) and mean lung dose in stage III patients with inhomogeneous hypoperfusion. If the dose to FL is shown to be the determinant of lung toxicity, IMRT would allow for effective dose escalation by specific avoidance of functional lung.
机译:比较了25例非小细胞肺癌(NSCLC)患者的IMRT和3D适形放疗(3-DCRT)计划,根据计划目标体积(PTV)覆盖范围和SPECT灌注确定的功能肺(FL)保留度扫描。 IMRT导致III期不均匀灌注不足的患者的功能性V(20)和平均肺部剂量显着降低。如果显示出FL的剂量是肺毒性的决定因素,那么IMRT可以通过避免特定的功能性肺部来提高有效剂量。

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