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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >The integration of PET-CT scans from different hospitals into radiotherapy treatment planning.
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The integration of PET-CT scans from different hospitals into radiotherapy treatment planning.

机译:将来自不同医院的PET-CT扫描整合到放射治疗计划中。

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PURPOSE: To integrate PET-CT scans from different hospitals into radiotherapy treatment planning. METHODS AND MATERIALS: A cylindrical phantom with spheres of different diameters was scanned on three different Siemens Biograph PET-CT scanners in three hospitals. The spheres and cylinder were filled with 18F-FDG such that different sphere-to-background (S/B) ratios were obtained. Scans were analyzed using dedicated software for automated delineation based on standardized uptake value (SUV) and using different reconstruction parameters. RESULTS: SUV thresholding curves for different S/B ratios were obtained for the different scanners. Differences in SUV auto-contouring thresholds were found to be significant for PET-CT simulators from different radiotherapy and nuclear medicine departments. A change in PET reconstruction parameters showed a significant effect on the results. CONCLUSION: Synchronization of PET-CT imaging protocols between cooperating hospitals is important for reliable determination of SUV auto-contouring thresholds. Whenever this goal has been achieved automated SUV delineation based on a S/B ratio using PET-CT images from different institutions can reliably be performed using individually determined threshold curves.
机译:目的:将来自不同医院的PET-CT扫描整合到放射治疗计划中。方法和材料:在三家医院的三台不同的Siemens Biograph PET-CT扫描仪上扫描了具有不同直径球体的圆柱体模。用18F-FDG填充球体和圆柱体,从而获得不同的球体与背景(S / B)比。使用专用软件根据标准摄取值(SUV)并使用不同的重建参数对扫描进行分析,以进行自动描绘。结果:对于不同的扫描仪,获得了不同S / B比的SUV阈值曲线。对于来自不同放射治疗和核医学部门的PET-CT模拟器,发现SUV自动轮廓阈值的差异非常显着。 PET重建参数的变化显示出对结果的显着影响。结论:合作医院之间PET-CT成像协议的同步对于确定SUV自动轮廓阈值至关重要。只要实现了这一目标,就可以使用单独确定的阈值曲线可靠地执行来自S / B比率的SUV轮廓自动确定,使用来自不同机构的PET-CT图像进行。

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