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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Dosimetric evaluation of prostate rotations and their correction by couch rotations.
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Dosimetric evaluation of prostate rotations and their correction by couch rotations.

机译：前列腺旋转的剂量学评估及其通过卧榻旋转的矫正。

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摘要

PURPOSE: To investigate the dosimetric effect of prostate rotations and limited on-line corrections by couch rotations (3 degrees ) for prostate, seminal vesicles and organs at risk. METHODS: For 5 patients IMRT plans were made, treating the prostate plus base of the seminal vesicles. Realistic and idealised dose distributions were considered, the latter demonstrating extreme effects for rotations and their corrections. Translation errors were assumed to be corrected on-line. For each patient 20 treatments with different rotation errors were simulated: 20 systematic errors were generated and 20 times 35 random deviations were superimposed to simulate day-to-day variations. Using a research module of PLATO-RTS treatments with rotation errors, with and without on-line corrections, were simulated. RESULTS: The largest dosimetric effect of rotation errors and corrections was found for the seminal vesicles with idealised dose distribution: coverage improved from 92.6% (range 89.9-96.0%) to 95.9% (94.7-98.1%). The gain for the idealised prostate was less: 95.9% (94.4-97.0%) to 97.5% (95.5-98.4%). For the femoral heads the dose increase could be as large as 12.2% (6.2-19.3%). CONCLUSIONS: On-line correction of rotations can improve target coverage slightly. For organs at risk at a large distance from the isocentre the result can be a significant increase in dose.
机译：目的：研究前列腺旋转的剂量效应，以及对有风险的前列腺，精囊和器官进行卧榻旋转（3度）的有限在线校正。方法：为5例患者制定了IMRT计划，治疗了前列腺加上精囊根部。考虑了现实和理想的剂量分布，后者显示了旋转及其修正的极端影响。假定翻译错误已在线纠正。对于每位患者，模拟了20种具有不同旋转误差的治疗方法：产生了20种系统误差，并叠加了20次35次随机偏差以模拟每日变化。使用带有旋转误差的PLATO-RTS处理的研究模块，对有无在线校正进行了模拟。结果：对于具有理想剂量分布的精囊，旋转误差和矫正的最大剂量效应被发现：覆盖率从92.6％（范围89.9-96.0％）提高到95.9％（94.7-98.1％）。理想化的前列腺的增益较小：95.9％（94.4-97.0％）至97.5％（95.5-98.4％）。对于股骨头，剂量增加可能高达12.2％（6.2-19.3％）。结论：在线旋转校正可以稍微改善目标覆盖率。对于距离等距点很远的高风险器官，结果可能是剂量的显着增加。

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