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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >The delineation of target volumes for radiotherapy of lung cancer patients.
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The delineation of target volumes for radiotherapy of lung cancer patients.

机译：划定了肺癌患者放疗的目标量。

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PURPOSE: Differences in the delineation of the gross target volume (GTV) and planning target volume (PTV) in patients with non-small-cell lung cancer are considerable. The focus of this work is on the analysis of observer-related reasons while controlling for other variables. METHODS: In three consecutive patients, eighteen physicians from fourteen different departments delineated the GTV and PTV in CT-slices using a detailed instruction for target delineation. Differences in the volumes, the delineated anatomic lymph node compartments and differences in every delineated pixel of the contoured volumes in the CT-slices (pixel-by-pixel-analysis) were evaluated for different groups: ten radiation oncologists from ten departments (ROs), four haematologic oncologists and chest physicians from four departments (HOs) and five radiation oncologists from one department (RO1D). RESULTS: Agreement (overlap > or = 70% of the contoured pixels) for the GTV and PTV delineation was found in 16.3% and 23.7% (ROs), 30.4% and 38.6% (HOs) and 32.8% and 35.9% (RO1D), respectively. CONCLUSION: A large interobserver variability in the PTV and much more in the GTV delineation were observed in spite of a detailed instruction for delineation. The variability was smallest for group ROID where due to repeated discussions and uniform teaching a better agreement was achieved.
机译：目的：在非小细胞肺癌患者的总目标量（GTV）和计划目标量（PTV）的划分上存在很大差异。这项工作的重点是在控制其他变量的同时分析与观察者相关的原因。方法：在连续的三例患者中，来自十四个不同部门的十八名医生使用详细的目标划定说明在CT切片中划定了GTV和PTV。针对不同组评估了CT切片的体积差异，划定的解剖淋巴结腔室以及轮廓体积的每个划定像素的差异（逐像素分析）：来自十个科室（RO）的十位放射肿瘤学家，来自四个部门（HOs）的四名血液肿瘤医师和胸部医师以及来自一个部门（RO1D）的五名放射肿瘤学家。结果：GTV和PTV轮廓的一致性（重叠>或=轮廓像素的70％）分别占16.3％和23.7％（RO），30.4％和38.6％（HOs），32.8％和35.9％（RO1D） ， 分别。结论：尽管有详细的划定说明，但在PTV中观察者之间存在较大差异，而在GTV划定中观察到的差异更大。 ROID组的差异最小，由于反复讨论和统一教学，达成了更好的协议。

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