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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Dosimetric and geometric evaluation of an open low-field magnetic resonance simulator for radiotherapy treatment planning of brain tumours.
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Dosimetric and geometric evaluation of an open low-field magnetic resonance simulator for radiotherapy treatment planning of brain tumours.

机译：开放性低场磁共振模拟器的剂量和几何评估，用于脑肿瘤放射治疗计划。

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摘要

BACKGROUND AND PURPOSE: Magnetic resonance (MR) imaging is superior to computed tomography (CT) in radiotherapy of brain tumours. In this study an open low-field MR-simulator is evaluated in order to eliminate the cost of and time spent on additional CT scanning. MATERIALS AND METHODS: Eleven patients with brain tumours are both CT and MR scanned and the defined tumour volumes are compared. Image distortions and dose calculations based on CT density correction, MR unit density and MR bulk density, bone segmentation are performed. Monte Carlo simulations using 4 and 8 MV beams on homogeneous and bone segmented mediums are performed. RESULTS: Mean MR and CT tumour volumes of approximately the same size (V MR 55+/-34 cm3 and V CT small intersection volumes are observed. The MR images show negligible distortion within radial distances below 12 cm (<1.5 mm). On unit density mediums, dose errors above 2% are observed in low dose areas. Monte Carlo simulations with 4 MV photons show large deviations in dose (>2%) just behind the skull if bone is not segmented. CONCLUSIONS: It is feasible to use an MR-simulator for radiotherapy planning of brain tumours if bone is segmented or a careful choice of beam energy (>4 MV) is selected.
机译：背景与目的：在脑肿瘤的放射治疗中，磁共振（MR）成像优于计算机断层扫描（CT）。在这项研究中，对开放式低场MR模拟器进行了评估，以消除额外CT扫描的成本和时间。材料与方法：对11例脑肿瘤患者进行了CT和MR扫描，并对定义的肿瘤体积进行了比较。进行基于CT密度校正，MR单位密度和MR堆积密度，骨分割的图像失真和剂量计算。使用均质和骨分段介质上的4和8 MV束进行蒙特卡洛模拟。结果：MR和CT的平均肿瘤体积大致相同（V MR 55 +/- 34 cm3和V CT较小的交叉体积），MR图像显示在径向距离小于12 cm（<1.5 mm）内的变形可忽略不计。单位密度的介质，在低剂量区域观察到2％以上的剂量误差。如果对4个MV光子进行蒙特卡洛模拟，则如果不分割骨骼，正好在头骨后面的剂量存在较大偏差（> 2％）。如果骨骼被分割或选择了束能量（> 4 MV）的仔细选择，则可以使用MR仿真器对脑肿瘤进行放射治疗计划。

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