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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Results of fiberoptic endoscopic evaluation of swallowing vs. radiation dose in the swallowing muscles after radiotherapy of cancer in the oropharynx.
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Results of fiberoptic endoscopic evaluation of swallowing vs. radiation dose in the swallowing muscles after radiotherapy of cancer in the oropharynx.

机译：纤维内窥镜评估口咽癌放疗后吞咽肌肉与吞咽肌肉辐射剂量的结果。

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摘要

BACKGROUND AND PURPOSE: Dysphagia is a serious complaint but frequently underreported. This paper assesses for oropharyngeal cancer (OPC) the relationship between the dose received by the swallowing structures, and the findings of a fiberoptic endoscopic evaluation of the swallowing process (FEES). MATERIALS AND METHODS: Between 2000 and 2005, 60 of 67 OPC patients local-regionally NED for at least one year following treatment responded to three types of QoL questionnaires; i.e. Performance Status Scales, EORTC H&N35, and M.D. Anderson Dysphagia Inventory. Twenty-four patients agreed to the FEES procedure. The main swallowing muscles were delineated, with the mean dose per muscle calculated using the original 3D CT-based treatment plans. Regression analysis was performed between FEES variables and the doses in the different swallowing muscles and the dysphagia related questionnaires. RESULTS: A significant relationship was found between the results of FEES and the mean dose in the superior constrictor muscle (SCM). Some of the subjective dysphagia complaints were significantly correlated with the FEES variables in this retrospectively study. CONCLUSION: A higher dose in the SCM generally results in worsening of the findings obtained by the FEES examination.
机译：背景与目的：吞咽困难是一种严重的不适，但经常被低估。本文评估吞咽结构所接受的剂量与咽部过程的光纤内窥镜评估结果之间的关系，以评估口咽癌（OPC）。材料与方法：在2000年至2005年之间，治疗后至少一年的67名OPC局部或局部NED患者中有60名对三种QoL问卷做出了回应。即绩效状态量表，EORTC H＆N35和M.D. Anderson吞咽困难量表。 24名患者同意FEES程序。画出主要的吞咽肌肉，并使用原始的基于3D CT的治疗计划计算出每只肌肉的平均剂量。在FEES变量与不同吞咽肌肉的剂量和吞咽困难相关问卷之间进行回归分析。结果：FEES结果与上缩窄肌（SCM）的平均剂量之间存在显着关系。在这项回顾性研究中，一些主观吞咽困难主诉与FEES变量显着相关。结论：更高剂量的SCM通常会导致FEES检查发现的结果恶化。

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