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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Clinical radiation doses for spinal cord: the 1998 international questionnaire.
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Clinical radiation doses for spinal cord: the 1998 international questionnaire.

机译:脊髓的临床放射剂量:1998年国际调查表。

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BACKGROUND AND PURPOSE: Emmanuel van der Schueren gave a keynote lecture at the 1988 ASTRO annual conference pointing out that the spinal cord 'tolerance doses' then prescribed were probably unnecessarily cautious, resulting in probable underdosing of some tumours. This lecture was supported both by an international questionnaire which he and two of the present authors had conducted, and by animal experimental data. In 1997 he initiated a 10-year follow-up questionnaire, the results of which are summarised here. MATERIALS AND METHODS: The present report analyses the change in prescriptions from 1988 to 1998 and the variation in prescriptions among various regions of the World. RESULTS AND CONCLUSIONS: The main conclusion is that prescribed dose levels have increased significantly in this period. Large geographical variations still exist. Among responders who use a formula to correct for changed dose per fraction, 90% are now using the linear-quadratic model vs. 33% in 1988. The current status of clinically acceptable doses to spinal cord in 2-Gy fractions is discussed briefly. Further details from the responses to the 1998 questionnaire will be presented in another publication.
机译:背景与目的:伊曼纽尔·范·德·舒伦(Emmanuel van der Schueren)在1988年ASTRO年会上作了主题演讲,指出当时开出的脊髓“耐受剂量”可能是不必要的谨慎,可能导致某些肿瘤的剂量不足。他和他的两位作者进行的国际调查问卷以及动物实验数据都为这次演讲提供了支持。 1997年,他发起了一项为期10年的后续调查表,其结果在此处进行了总结。材料与方法:本报告分析了1988年至1998年处方的变化以及世界各地区处方的变化。结果与结论:主要结论是,在此期间,规定的剂量水平已显着增加。仍然存在较大的地域差异。在使用公式来校正每小部分剂量变化的响应者中,现在有90%的人使用线性二次模型,而1988年为33%。简要讨论了2-Gy分数中临床可接受的脊髓剂量的现状。对1998年调查表的答复中的进一步细节将在另一份出版物中提出。

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