Management of chemo/radiation-induced oral mucositis in patients with head and neck cancer: A review of the current literature

Moslemi Dariush; Nokhandani Akram Mohammadi; Otaghsaraei Mahsa Taheri; Moghadamnia Yasaman; Kazemi Sohrab; Moghadamnia Ali Akbar

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Management of chemo/radiation-induced oral mucositis in patients with head and neck cancer: A review of the current literature

机译：头颈部癌患者化学/放射诱发的口腔粘膜炎的治疗：当前文献综述

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Oropharyngeal mucositis is an important complication in non-surgical cancer treatments. It represents the major complication in radiotherapy of tumors located in head and neck areas. Many results have been published in order to define the best clinical protocol for prophylaxis or treatment of mucositis, but a consensus has not been attained yet. In this review, some recent topics in prophylaxis and treatment of mucositis related to radiation therapy are reconsidered using PUBMED and GOOGLE SCHOOLAR search engines from 2000 to 2015. In this review, more than 100 clinical studies have been selected and divided into the prophylactic or therapeutic uses of the evaluated treatment agents. The number of patients and kind of study design, the clinical features, prevalence, risk factors, pathogenesis, diagnosis, complication, prophylaxis and the treatment of mucositis were also specified. Nevertheless, it has not been truly achieved a consensus protocol of prophylaxis and treatment Of oral mucositis. (C) 2016 Elsevier Ireland Ltd. All rights reserved.

机译：口咽粘膜炎是非手术癌症治疗中的重要并发症。它代表了位于头颈部区域的肿瘤放疗的主要并发症。为了定义预防或治疗粘膜炎的最佳临床方案，已经发表了许多结果，但是尚未达成共识。在这篇综述中，从2000年到2015年，使用PUBMED和GOOGLE SCHOOLAR搜索引擎重新考虑了与放射疗法有关的粘膜炎的预防和治疗的一些最新话题。在这篇综述中，我们选择了100多项临床研究，分为预防性或治疗性被评估的治疗剂的用途。还规定了患者人数和研究设计种类，临床特征，患病率，危险因素，发病机理，诊断，并发症，预防和粘膜炎的治疗。然而，尚未真正达成预防和治疗口腔粘膜炎的共识方案。（C）2016 Elsevier Ireland Ltd.保留所有权利。

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《Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology》 |2016年第1期|共8页
作者
Moslemi Dariush; Nokhandani Akram Mohammadi; Otaghsaraei Mahsa Taheri; Moghadamnia Yasaman; Kazemi Sohrab; Moghadamnia Ali Akbar;
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正文语种 eng
中图分类肿瘤学;
关键词
Oral mucositis; Radiotherapy; Irradiation; Oropharyngeal; Cancer;

机译：口腔粘膜炎;放射治疗;放射线;口咽;癌症;

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1. Management of chemo/radiation-induced oral mucositis in patients with head and neck cancer: A review of the current literature [J] . Moslemi Dariush, Nokhandani Akram Mohammadi, Otaghsaraei Mahsa Taheri, Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology . 2016,第1期

机译：头颈部癌患者化学/放射诱发的口腔粘膜炎的治疗：当前文献综述
2. Randomized Double-Blind, Placebo-Controlled Phase III trial Evaluating the Effect of Oral Glutamine on Radiation-Induced Oral Mucositis and Neck Dermatitis in Head and Neck Cancer Patients [J] . Lee H. H., Huang C. J., Huang M. Y., International Journal of Radiation Oncology, Biology, Physics . 2018,第3Suppla期

机译：随机双盲，安慰剂对照期III试验评估口服谷氨酰胺对头颈癌症患者辐射诱导的口腔粘膜皮炎和颈部皮炎的影响
3. Oral Glutamine May Have No Clinical Benefits to Prevent Radiation-Induced Oral Mucositis in Adult Patients With Head and Neck Cancer: A Meta-Analysis of Randomized Controlled Trials [J] . Shuai Ting, Tian Xu, Xu Ling-Li, Frontiers in Nutrition . 2020,第4期

机译：口服谷氨酰胺可能没有临床益处，以防止辐射诱导的头部患者头部和颈部癌症中的口腔粘膜炎：随机对照试验的META分析
4. Low Level Laser Therapy in the Treatment of Oral Mucositis in Cancer Patients: Systematic Review of Literature [C] . RulaFawzi El-Sabbagh, Wayne J Selting Congress of the World Federation for Laser Dentistry . 2016

机译：低水平激光治疗治疗癌症患者口腔粘膜炎：文学系统综述
5. A comprehensive assessment of mucositis due to radiation for head and neck cancer: Pathophysiology, clinical and patient-reported outcomes, and a proposal for a novel treatment based on ayurvedic medicine. [D] . Ramnath, Rajesh. 2016

机译：头颈部癌放疗引起的粘膜炎的综合评估：病理生理，临床和患者报告的结局，以及基于阿育吠陀医学的新型治疗方案的建议。
6. Effects of a bioadhesive barrier-forming oral liquid on pain due to radiation-induced oral mucositis in patients with head and neck cancer: A randomized crossover preliminary study [O] . Sakiko Soutome, Souichi Yanamoto, Yumiko Kawashita, 2021

机译：生物粘附性障碍口腔液体对头颈癌患者辐射诱导的口腔粘液炎疼痛的影响：随机交叉初步研究
7. Randomized Double-Blind, Placebo-Controlled Phase III trial Evaluating the Effect of Oral Glutamine on Radiation-Induced Oral Mucositis and Neck Dermatitis in Head and Neck Cancer Patients [O] . H.H. Lee, C.J. Huang, M.Y. Huang, 2018

机译：随机双盲，安慰剂对照期III试验评估口服谷氨酰胺对头颈癌症患者辐射诱导的口腔粘膜皮炎和颈部皮炎的影响

Management of chemo/radiation-induced oral mucositis in patients with head and neck cancer: A review of the current literature

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