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首页> 外文期刊>Retina >Retinal thickness analysis(RTA): an objective method to assess and quantify the retinal thickness in healthy controls and in diabetics without diabetic retinopathy.
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Retinal thickness analysis(RTA): an objective method to assess and quantify the retinal thickness in healthy controls and in diabetics without diabetic retinopathy.

机译:视网膜厚度分析(RTA):一种评估和量化健康对照组和无糖尿病性视网膜病变的糖尿病患者视网膜厚度的客观方法。

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BACKGROUND: Since it has been shown that photocoagulation is indicated in patients with diabetic macular edema, quantitative and objective assessment of retinal thickness is of clinical importance. METHODS: A laser slit beam was projected on the retina and scanned across a 2 x 2 mm retinal area in 200 msec. Nine type 1 and 2 diabetic patients without funduscopically and photographically visible diabetic retinopathy and 10 healthy controls were scanned with the RTA. The intraindividual and interindividual variabilities of the RTA were determined. RESULTS: The intraindividual and interindividual variability was 5 microm and 15 microm, respectively. The mean value of the mean foveal thickness (MFT) and perifoveal retinal thickness (PFT) in the 10 healthy controls was 152 +/- 15 microm and 175 +/- 14 microm, respectively, and 181 +/- 26 microm and 191 +/- 27 microm, respectively, in the group of nine diabetics without signs of diabetic retinopathy. The MFT in the group of diabetic patients was significantly (P < 0.001) larger than in the control groups. CONCLUSION: Retinal thickness in diabetic patients without diabetic retinopathy was increased in all measurements in comparison with the findings in healthy subjects. Retinal thickness measurements with the RTA could possibly detect early signs of diabetic retinopathy before funduscopic and photographic signs are visible and may be helpful in guiding treatment.
机译:背景:由于已经显示糖尿病黄斑水肿患者需要进行光凝治疗,因此对视网膜厚度进行定量和客观评估具有重要的临床意义。方法:激光裂隙光束投射到视网膜上,并在200毫秒内扫描2 x 2 mm的视网膜区域。使用RTA扫描9例没有眼底镜和照相可见的糖尿病性视网膜病变的1型和2型糖尿病患者以及10名健康对照。确定了RTA的个体内和个体间差异。结果:个体内和个体间变异分别为5微米和15微米。 10个健康对照组的平均中央凹厚度(MFT)和中央凹视网膜厚度(PFT)的平均值分别为152 +/- 15微米和175 +/- 14微米,以及181 +/- 26微米和191 +在没有糖尿病性视网膜病变迹象的九位糖尿病患者中,分别为-/-27微米。糖尿病患者组的MFT明显高于对照组(P <0.001)。结论:与健康受试者相比,所有无糖尿病视网膜病变的糖尿病患者的视网膜厚度均增加。在眼底镜和照相征兆可见之前,使用RTA测量视网膜厚度可能可以检测出糖尿病性视网膜病变的早期征兆,可能有助于指导治疗。

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