HEF1-aurora A interactions: points of dialog between the cell cycle and cell attachment signaling networks.

Pugacheva EN; Golemis EA

首页> 外文期刊>Cell cycle >HEF1-aurora A interactions: points of dialog between the cell cycle and cell attachment signaling networks.

【24h】

HEF1-aurora A interactions: points of dialog between the cell cycle and cell attachment signaling networks.

机译：HEF1-aurora A相互作用：细胞周期与细胞附着信号网络之间的对话点。

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Regulated timing of cell division cycles, and geometrical precision in the planar orientation of cell division, are critical during organismal development and remain important for the maintenance of polarized structures in adults. Mounting evidence suggests that these processes are coordinated at the centrosome through the action of proteins that mediate both cell cycle and cell attachment. Our recent work identifying HEF1 as an activator of the Aurora A kinase suggests a novel hub for such integrated signaling. We suggest that defects in components of the machinery specifying the temporal and spatial integration of cell division may induce cancer and other diseases through pleiotropic effects on cell migration, proliferation, apoptosis, and genomic stability.

机译：调节细胞分裂周期的时间，以及细胞分裂的平面方向的几何精度，在有机体发育过程中至关重要，并且对于维持成年人的极化结构仍然很重要。越来越多的证据表明，这些过程通过介导细胞周期和细胞附着的蛋白质的作用在中心体上协调。我们最近的研究将HEF1识别为Aurora A激酶的激活剂，提示了这种整合信号的新型枢纽。我们建议指定细胞分裂的时间和空间整合的机制的组件中的缺陷可能通过对细胞迁移，增殖，凋亡和基因组稳定性的多效性作用诱导癌症和其他疾病。

著录项

来源
《Cell cycle》 |2006年第4期|共8页
作者
Pugacheva EN; Golemis EA;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类细胞生物学;
关键词
Cell Cycle; Phosphoproteins; Protein-Serine-Threonine Kinases; 细胞周期; 磷蛋白类; 蛋白质丝氨酸苏氨酸激酶;

机译：Cell Cycle;Phosphoproteins;Protein-Serine-Threonine Kinases;细胞周期;磷蛋白类;蛋白质丝氨酸苏氨酸激酶;

相似文献

外文文献
中文文献
专利

1. HEF1-aurora A interactions: points of dialog between the cell cycle and cell attachment signaling networks. [J] . Pugacheva EN, Golemis EA Cell cycle . 2006,第4期

机译：HEF1-aurora A相互作用：细胞周期与细胞附着信号网络之间的对话点。
2. Mutual interaction between endothelial cells and mural cells enhances BMP9 signaling in endothelial cells Mutual interaction between endothelial cells and mural cells enhances BMP9 signaling in endothelial cells Mutual interaction between endothelial cells and mural cells enhances BMP9 signaling in endothelial cells [J] . Yuki Tachida, Toyo Sakurai, Nanae Izumi, Biology Open . 2017,第3期

机译：内皮细胞和壁细胞之间的相互作用增强了内皮细胞中的BMP9信号传导内皮细胞和壁细胞之间的相互作用增强了内皮细胞中的BMP9信号传导。
3. KSHV gB associated RGD interactions promote attachment of cells by inhibiting the potential migratory signals induced by the disintegrin-like domain [J] . Hosni A. M. Hussein, Lia R. Walker, Shaw M. Akula BMC Cancer . 2016,第1期

机译：KSHV gB相关的RGD相互作用通过抑制由整合素样结构域诱导的潜在迁移信号来促进细胞附着
4. Observation of live cells' attachment, spreading, and drug interactions using metasurface-enhanced infrared reflection spectroscopy [C] . Steven H. Huang, Shourya Dutta Gupta, Robert Delgado, Optical Biopsy XVII: Toward Real-Time Spectroscopic Imaging and Diagnosis . 2019

机译：使用超表面增强红外反射光谱法观察活细胞的附着，扩散和药物相互作用
5. The expression of G(1) cell cycle related proteins in resting and cycling B cells following delivery of bar- and T helper cell-derived signals. [D] . Mullins, Melisa Wren. 1997

机译：G（1）细胞周期相关蛋白在传递bar和T辅助细胞衍生信号后在静止和循环B细胞中的表达。
6. HEF1-Aurora A interactions: points of dialog between the cell cycle and cell attachment signaling networks [O] . Elena N. Pugacheva, Erica A. Golemis -1

机译：HEF1-Aurora A相互作用：细胞周期与细胞附着信号网络之间的对话点
7. KSHV gB associated RGD interactions promote attachment of cells by inhibiting the potential migratory signals induced by the disintegrin-like domain [O] . 2016

机译：KSHV gB相关的RGD相互作用通过抑制由整合素样结构域诱导的潜在迁移信号来促进细胞附着

HEF1-aurora A interactions: points of dialog between the cell cycle and cell attachment signaling networks.

摘要

著录项

相似文献

相关主题

期刊订阅