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Apolipoprotein D: an overview of its role in aging and age-related diseases.

机译:载脂蛋白D:概述其在衰老和与年龄有关的疾病中的作用。

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摘要

Seymour Benzer's curiosity was legendary and seemingly limitless. Towards the end of his life, one of the (many) questions that kept him awake at night concerned the emerging role of Apolipoprotein D (ApoD) in aging and neurological disease. In this perspective, we will discuss the clinical and biochemical data on ApoD, and the input from the recent genetic studies in model systems, including those from the Benzer lab.
机译:西摩·本泽(Seymour Benzer)的好奇心极富传奇色彩,看似无限。在他生命的尽头,使他彻夜难眠的(许多)问题之一涉及载脂蛋白D(ApoD)在衰老和神经系统疾病中的新兴作用。从这个角度出发,我们将讨论有关ApoD的临床和生化数据,以及模型系统中最近的遗传研究(包括来自Benzer实验室的研究)的输入。

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