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Regenerative medicine Clinical relevance, implications and limitations of the stem cell-based therapies

机译:再生医学基于干细胞疗法的临床意义,意义和局限性

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摘要

Many believe that success of the concept of regenerative medicine critically depends on our unlimited access to the human embryonic stem cells for scientific and therapeutic applications. Recent ground breaking studies seem to challenge this broadly held view by demonstrating a remarkable healing power of mammalian adult (somatic) stem cells. However, mounting evidence of involvement of sternness pathways in development of therapy-resistant metastatic cancers argue for more careful considerations of potential risk and benefits associated with the stem cell-based therapies.
机译:许多人认为,再生医学概念的成功关键取决于我们无限地利用人类胚胎干细胞进行科学和治疗应用。最近的突破性研究似乎通过证明哺乳动物成体(体)干细胞具有非凡的治愈能力,挑战了这一观点。然而,越来越多的证据表明,在治疗耐药的转移性癌症的发展中涉及到严厉性途径,因此,人们对基于干细胞疗法的潜在风险和益处进行了更为仔细的考虑。

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