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Linear energy transfer dependence of Al2O3:C optically stimulated luminescence detectors exposed to therapeutic proton beams

机译：暴露于治疗性质子束的Al2O3：C光学激发发光探测器的线性能量转移依赖性

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摘要

Currently, there are no radiation detectors that can be used for routine measurements of linear energy transfer (LET) in particle therapy clinics. In this work, we characterized the LET dependence of Al2O3:C optically stimulated luminescence (OSL) detectors (OSLDs) exposed to therapeutic proton beams in order to evaluate their potential for clinical LET measurements. We evaluated OSLDs that were irradiated with an absorbed dose to water of 0.2 Gy in therapeutic proton beams with average energies ranging between approximately 25 MeV and 200 MeV, resulting in LET in water values between 0.45 and 2.29 key/mu m. We examined two properties of the OSL emission signal in terms of LET dependence: the signal intensities of the blue and ultraviolet (UV) emission bands, and the shapes of the OSL curves. We found that the signal intensity of the UV emission band increased consistently with LET within the range investigated, whereas the intensity of the blue emission band remained constant. Our results also demonstrated that the OSL curve shapes were more LET dependent for signals containing both the blue and UV emission bands than for signals containing only one of the bands. Both metrics we examined in this study the relative UV/blue emission signal intensities and OSL curve shapes show potential for LET detection in proton therapy. (C) 2014 Elsevier Ltd. All rights reserved.
机译：当前，没有放射线检测器可用于粒子治疗诊所中的线性能量转移（LET）的常规测量。在这项工作中，我们表征了暴露于治疗性质子束的Al2O3：C光激发发光（OSL）检测器（OSLD）的LET依赖性，以评估其在临床LET测量中的潜力。我们评估了在治疗性质子束中以0.2 Gy的水吸收剂量辐照的OSLD，其平均能量在大约25 MeV和200 MeV之间，从而使水的LET值在0.45和2.29 key /μm之间。我们根据LET依赖关系检查了OSL发射信号的两个属性：蓝色和紫外线（UV）发射带的信号强度，以及OSL曲线的形状。我们发现，在所研究的范围内，UV发射带的信号强度与LET一致增加，而蓝色发射带的强度保持恒定。我们的结果还表明，与仅包含一个和两个波段的信号相比，对于同时包含蓝色和紫外线发射波段的信号，OSL曲线的形状更受LET的影响。我们在这项研究中检查的两个指标，相对的紫外线/蓝色发射信号强度和OSL曲线形状均显示出质子治疗中LET检测的潜力。 （C）2014 Elsevier Ltd.保留所有权利。

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