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首页> 外文期刊>Respirology : >Clinical characteristics and efficacy of bronchoscopic intervention for tracheobronchial leiomyoma.
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Clinical characteristics and efficacy of bronchoscopic intervention for tracheobronchial leiomyoma.

机译：支气管镜治疗气管支气管平滑肌瘤的临床特点和疗效。

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BACKGROUND AND OBJECTIVE: This study reports the clinical characteristics, efficacy and safety of bronchoscopic treatment of patients with tracheobronchial leiomyoma. METHODS: A retrospective study of 10 patients with tracheobronchial leiomyoma who underwent bronchoscopic intervention between 2000 and 2007 at a single centre, documenting the clinical characteristics, treatment method and outcomes. RESULTS: Seven men and three women were studied. The median age at diagnosis was 47 years (range 17-66). The most frequent symptoms were cough (n = 5) and dyspnoea (n = 4). The lesions were in the trachea in two patients, the right bronchi in six, and the left bronchi in two. On chest CT, the most frequent findings were a tracheobronchial mass without parenchymal lesion (n = 7). The tumours were removed by neodymium-yttrium-aluminum-garnet laser treatment by rigid bronchoscopy under general anaesthesia (n = 9) and with flexible bronchoscopy under local (n = 1) anaesthesia. Two patients eventually underwent surgical resection because of late tumour recurrence at 16 months, after the bronchoscopic intervention, in one patient, and incomplete removal by bronchoscopic intervention in another patient. In eight of ten patients who were successfully treated by the bronchoscopic intervention, the clinical outcome was good during the median follow-up period of 24.5 months. There were no procedure-related mortalities or late complications. CONCLUSIONS: Patients with a tracheobronchial leiomyoma usually present with non-specific respiratory symptoms and an endobronchial mass without parenchymal lesions. Bronchoscopic intervention is a safe and effective technique for the treatment of patients with a tracheobronchial leiomyoma.
机译：背景与目的：本研究报道了支气管镜治疗气管支气管平滑肌瘤的临床特点，疗效和安全性。方法：回顾性研究2000年至2007年在同一中心接受支气管镜干预的10例气管支气管平滑肌瘤患者的临床特征，治疗方法和结果。结果：研究了7名男性和3名女性。诊断时的中位年龄为47岁（范围17-66）。最常见的症状是咳嗽（n = 5）和呼吸困难（n = 4）。病变在气管中的两个患者中，右支气管中的六个，左支气管中的两个。在胸部CT上，最常见的发现是无实质性病变的气管支气管肿块（n = 7）。钕-钇-铝石榴石激光在全身麻醉下（n = 9）进行硬性支气管镜检查，在局部麻醉下（n = 1）进行柔性支气管镜检查，去除肿瘤。由于一名患者在支气管镜干预后16个月肿瘤复发较晚，而另一名患者由于支气管镜未完全切除而导致两名患者最终接受手术切除。在经支气管镜干预成功治疗的十位患者中，有八位在中位随访24.5个月期间临床效果良好。没有与手术相关的死亡率或晚期并发症。结论：气管支气管平滑肌瘤患者通常表现为非特异性呼吸道症状，支气管内肿块无实质性病变。支气管镜干预是治疗气管支气管平滑肌瘤的一种安全有效的技术。

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