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首页> 外文期刊>Reviews in Fisheries Science & Aquaculture >Maternal Thyroid and Glucocorticoid Hormone Interactions in Larval Fish Development, and Their Applications in Aquaculture
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Maternal Thyroid and Glucocorticoid Hormone Interactions in Larval Fish Development, and Their Applications in Aquaculture

机译:幼体鱼类发育中的母体甲状腺激素和糖皮质激素激素相互作用及其在水产养殖中的应用

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Thyroid hormones (THs) have long been known to have regulatory roles in the differentiation and maturation of vertebrate embryos, beginning with the knowledge that hormones of maternal origin are essential for human fetal central nervous and respiratory system development. Precise measurements of circulating THs led to insights into their critically important actions throughout vertebrate growth and development, initially with amphibian metamorphosis and including embryogenesis in fishes. Thyroid cues for larval fish differentiation are enhanced by glucocorticoid hormones, which promote deiodinase activity and thereby increase the generation of triiodothyronine (T-3) from the less bioactive thyroxin (T-4). Glucocorticoids also induce the expression of thyroid hormone receptors in some vertebrates. Maternally derived thyroid hormones and cortisol are deposited in fish egg yolk and accelerate larval organ system differentiation until larvae become capable of endogenous endocrine function. Increases in the T-3/T-4 ratio during larval development may reflect the regulatory importance of maternal thyroid hormones. Experimental applications of individual hormones have produced mixed results, but treatments with combinations of thyroid and corticoid hormones consistently promote larval fish development and improve survival rates. The developmental and survival benefits of maternal endocrine provisioning are increased in viviparous fishes, in which maternal/larval chemical contact is prolonged. Treatments with exogenous thyroid and corticoid hormones consistently promote development and reduce mortality rates in larval fishes, with potential hatchery-scale applications in aquaculture.
机译:早就知道甲状腺激素(THs)在脊椎动物胚胎的分化和成熟中起调节作用,首先要知道母源激素对于人类胎儿中枢神经和呼吸系统的发育至关重要。对循环TH的精确测量导致人们洞悉它们在整个脊椎动物的生长和发育过程中至关重要的作用,最初是两栖类变态,包括鱼类的胚胎发生。糖皮质激素可增强幼虫分化的甲状腺功能,从而促进去碘酶活性,从而增加生物活性较低的甲状腺素(T-4)生成三碘甲状腺素(T-3)的能力。糖皮质激素还诱导某些脊椎动物中甲状腺激素受体的表达。母体来源的甲状腺激素和皮质醇沉积在鱼卵黄中,并加速幼虫器官系统的分化,直到幼虫具有内源性内分泌功能。幼虫发育过程中T-3 / T-4比率的增加可能反映了母体甲状腺激素的调节重要性。各种激素的实验应用产生了不同的结果,但是甲状腺激素和皮质激素的联合治疗始终可以促进幼体鱼的发育并提高存活率。母体/幼体化学接触时间延长的胎生鱼增加了母体内分泌供给的发展和生存益处。外源性甲状腺和皮质类固醇激素的治疗​​持续促进幼体鱼的发育并降低其死亡率,在水产养殖中具有潜在的孵化规模应用。

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