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首页> 外文期刊>Biological trace element research >Levels of Heavy Metals and Trace Elements in Umbilical Cord Blood and the Risk of Adverse Pregnancy Outcomes: a Population-Based Study
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Levels of Heavy Metals and Trace Elements in Umbilical Cord Blood and the Risk of Adverse Pregnancy Outcomes: a Population-Based Study

机译：脐带血中重金属和微量元素的含量以及不良妊娠结局的风险：一项基于人群的研究

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摘要

To better understand the relationship between prenatal exposure to heavy metals and trace elements and the risk of adverse pregnancy outcomes, we investigated the status of heavy metals and trace elements level in a Chinese population by collecting umbilical cord blood. Umbilical cord blood heavy metals and trace elements concentrations were determined by inductively coupled plasma-mass spectrometry. No differences with statistical significance in the median arsenic (As), cadmium (Cd), cobalt (Co), chromium (Cr), copper (Cu), manganese (Mn), nickel (Ni), lead (Pb), strontium (Sr), thallium (Tl), vanadium (V), and zinc (Zn) concentrations were observed between the adverse pregnancy outcome group and the reference group. Titanium (Ti) and antimony (Sb) were found at higher levels with statistical significance in the cord blood samples with adverse pregnancy group when compared to the ones in the reference group. The association between Ti levels and the risk of adverse pregnancy outcomes remained significant after adjusting for potential confounding factors, including newborn weight. These results indicated that environmental exposure to Ti may increase the risk of adverse pregnancy outcomes in Chinese women without occupational exposure.
机译：为了更好地了解产前暴露于重金属和微量元素与不良妊娠结局风险之间的关系，我们通过收集脐带血调查了中国人群中重金属和微量元素水平的状况。通过电感耦合等离子体质谱法测定脐带血中的重金属和痕量元素的浓度。砷（As），镉（Cd），钴（Co），铬（Cr），铜（Cu），锰（Mn），镍（Ni），铅（Pb），锶（在不良妊娠结局组和参考组之间观察到Sr），th（Tl），钒（V）和锌（Zn）浓度。与参考组相比，妊娠不良组脐带血中的钛（Ti）和锑（Sb）含量较高，具有统计学意义。调整潜在的混杂因素（包括新生儿体重）后，Ti水平与不良妊娠结局风险之间的关联仍然很显着。这些结果表明，在没有职业暴露的情况下，环境中的Ti暴露可能会增加中国女性不良妊娠结局的风险。

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