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首页> 外文期刊>Reviews of environmental contamination and toxicology >Ecotoxicological evaluation of perfluorooctanesulfonate (PFOS).
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Ecotoxicological evaluation of perfluorooctanesulfonate (PFOS).

机译:全氟辛烷磺酸盐(PFOS)的生态毒理学评估。

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Based on available toxicity data, protective screening-level concentrations of PFOS were calculated for aquatic and terrestrial organisms. Using the Great Lakes Initiative, water concentrations of PFOS were calculated to protect aquatic plants and animals. The screening plant value (SPV) protective of aquatic algae and macrophytes was calculated as 2.3 mg PFOS/L. The secondary chronic value protective of aquatic organisms was 1.2 microg PFOS/L. The screening-value water concentrations less than or equal to 1.2 microg PFOS/L would not pose a potential risk to aquatic organisms. Because the aquatic benchmark is based on the most sensitive species, this benchmark should also be protective of other aquatic organisms, including amphibians. The tissue-based TRV for fish was determined to be 87 mg PFOS/kg ww. For terrestrial plants, a screening benchmark was determined to be 1.3 mg PFOS/kg soil ww or 1.5 mg PFOS/kg soil dw, whereas for soil invertebrates such as earthworms the benchmark value was 39 mg PFOS/kg dw soil or 33 mg PFOS/kgww soil. For avian species, dietary, ADI, and egg yolk-based benchmarks were determined as 0.28mg PFOS/kg diet, 0.021mg PFOS/kg bw/d, and 1.7 microg PFOS/mL yolk, respectively. Benchmarks for serum and liver for the protection of avian species were 1.0 microg PFOS/mL and 0.6 microg PFOS/gww, respectively. However, no-effect levels in laboratory studies suggest actual population-level effects would not be expected to occur until a concentration of 6.0mg PFOS/kg in the diet, 5.0 microg PFOS/gww in the liver, or 9.0 microg PFOS/mL in the serum was exceeded, thus indicating the conservative nature of the benchmarks.
机译:根据现有的毒性数据,计算了水生和陆地生物的全氟辛烷磺酸保护性筛选水平浓度。利用大湖区倡议,计算了全氟辛烷磺酸的水浓度以保护水生植物和动物。计算出的保护水生藻类和大型植物的筛选植物价值(SPV)为2.3 mg PFOS / L。对水生生物的次要慢性保护价值为1.2微克PFOS / L。筛选值水浓度小于或等于1.2微克PFOS / L不会对水生生物构成潜在风险。由于水生基准是最敏感的物种,因此该基准还应保护其他水生生物,包括两栖动物。鱼的基于组织的TRV确定为87 mg PFOS / kg ww。对于陆生植物,筛选基准确定为1.3 mg PFOS / kg土或1.5 mg PFOS / kg dw,而无脊椎动物(例如earth)的基准值为39 mg PFOS / kg dw土或33 mg PFOS / kgww土壤。对于禽类,饮食,ADI和蛋黄的基准分别确定为0.28mg PFOS / kg饮食,0.021mg PFOS / kg bw / d和1.7 microg PFOS / mL蛋黄。血清和肝脏保护鸟类的基准分别为1.0微克PFOS / mL和0.6微克PFOS / gww。但是,实验室研究中的无影响水平表明,除非饮食中的浓度为6.0mg PFOS / kg,肝脏中的浓度为5.0 microg PFOS / gww或饮食中的浓度为9.0 microg PFOS / mL,否则不会出现实际的人口水平影响。血清超过了,因此表明基准的保守性。

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