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首页> 外文期刊>Resuscitation. >Transoesophageal cardiac pacing is effective for cardiopulmonary resuscitation in a rat of asphyxial model.
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Transoesophageal cardiac pacing is effective for cardiopulmonary resuscitation in a rat of asphyxial model.

机译：经食管心脏起搏可有效地抑制窒息模型大鼠的心肺复苏。

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OBJECTIVE: To investigate effectiveness of transoesophageal cardiac pacing in a rat model of asphyxial cardiac arrest. METHODS: Ten minutes after the tracheal tube had been clamped, cardiac arrest (CA) occurred in 20 Sprague-Dawley rats, and the rats were assigned randomly to receive cardiopulmonary resuscitation (CPR) in a control group or CPR combined with transoesophageal cardiac pacing in a pacing group. Restoration of spontaneous circulation (ROSC) was defined as an unassisted pulse with a mean arterial pressure (MAP) of >or=20 mmHg for >or=1 min. RESULTS: ROSC was significantly more frequent in the pacing group compared with the control group (7/10 versus 1/10, P<0.05). Faster ROSC and longer survival trend in the pacing group were seen compared with the control group. CONCLUSION: Transoesophageal cardiac pacing is effective for CPR in a rat of asphyxial model. However, the precise mechanism is not clear and further experiments will be necessary.
机译：目的：探讨经食道心脏起搏在窒息性心脏骤停大鼠模型中的有效性。方法：夹住气管导管十分钟后，在20只Sprague-Dawley大鼠中发生心脏骤停（CA），将这些大鼠随机分为对照组或CPR联合经食道心脏起搏器接受心肺复苏（CPR）。起搏小组。恢复自发循环（ROSC）定义为平均动脉压（MAP）≥20 mmHg≥1 min的无辅助脉搏。结果：起搏组的ROSC明显高于对照组（7/10对1/10，P <0.05）。与对照组相比，起搏组的ROSC更快，生存趋势更长。结论：经食管心脏起搏对窒息模型大鼠的CPR有效。但是，确切的机理尚不清楚，将需要进一步的实验。

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