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首页> 外文期刊>Rheumatology >Costs of rheumatoid arthritis during the period 1990-2010: A register-based cost-of-illness study in Sweden
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Costs of rheumatoid arthritis during the period 1990-2010: A register-based cost-of-illness study in Sweden

机译：1990-2010年间类风湿关节炎的费用：瑞典基于登记册的疾病费用研究

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Objectives: The objectives of this study were to analyse the total socio-economic impact of RA in Sweden during the period 1990-2010 and to analyse possible changes in costs during this period. The period was deliberately chosen to cover 10 years before and 10 years after the introduction of biologic drugs. Methods: A prevalence-based cost-of-illness study was conducted based on data from national and regional registries. Results. There was a decrease in the utilization of RA-related inpatient care as well as sick leave and disability pension during 1990-2010 in Sweden. Total costs for RA are presented in current prices as well as inflation-adjusted with the consumer price index (CPI) and a healthcare price index. The total fixed cost of RA was ?454 million in 1990, adjusted to the price level of 2010 with the CPI. This cost increased to E600 million in 2010 and the increase was mainly due to the substantially increasing costs for pharmaceuticals. Of the total costs, drug costs increased from 3% to 33% between 1990 and 2010. Consequently the portion of total costs accounting for indirect costs for RA is lowered from 75% in 1990 to 58% in 2010. Conclusion: By inflation adjusting with the CPI, which is reasonable from a societal perspective, there was a 32% increase in the total fixed cost of RA between 1990 and 2010. This suggests that decreased hospitalization and indirect costs have not fallen enough to offset the increasing cost of drug treatment.
机译：目标：这项研究的目的是分析1990-2010年瑞典RA的总社会经济影响，并分析此期间成本的可能变化。故意选择的期限为在引入生物药物之前的10年和之后的10年。方法：基于来自国家和地区注册机构的数据，进行了基于患病率的疾病成本研究。结果。在1990-2010年期间，瑞典与RA有关的住院护理以及病假和伤残抚恤金的使用率有所下降。 RA的总成本以当前价格表示，并通过消费者价格指数（CPI）和医疗保健价格指数进行通胀调整。 1990年RA的固定成本总额为4.54亿英镑，根据CPI调整至2010年的价格水平。该费用在2010年增加到6亿欧元，主要是由于药品费用大幅增加。在总成本中，药品成本在1990年至2010年之间从3％增加到33％。因此，占RA间接成本的总成本部分从1990年的75％下降到2010年的58％。结论：从社会角度看，CPI合理，1990年至2010年RA的总固定成本增加了32％。这表明住院和间接成本的下降不足以抵消药物治疗成本的上升。

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