• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>RSC Advances >Surface modification of a PVDF membrane by cross-linked collagen
【24h】

Surface modification of a PVDF membrane by cross-linked collagen

机译：交联胶原蛋白对PVDF膜的表面改性

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A polyvinylidene fluoride (PVDF) membrane was modified by a low temperature plasma treatment and grafted with cross-linked collagen. The crosslinker of collagen was glutaraldehyde. The effects of glutaraldehyde concentration, crosslinking time and crosslinking temperature on membrane properties and surface structure were investigated. The properties of the modified membrane were characterized by the contact angle and pure water flux. The surface structure of the membrane dyed with an acid dye was observed by a polarizing microscope. The modified membrane was further characterized concerning permeability and adsorption capacity. Bovine serum albumin (BSA) was used as a model protein. The cell culture ability of the membrane was examined by the methyl thiazolyl tetrazolium (MTT) method. The amount of grafted collagen on the membrane surface reached the maximum when collagen was cross-linked with 0.4 wt% glutaraldehyde for 1 h at 35 degrees C. The BSA adsorption capacity and cell culture ability examination indicated that the PVDF membrane grafted with cross-linked collagen had good hydrophilicity and biocompatibility.
机译：聚偏二氟乙烯（PVDF）膜通过低温等离子体处理进行了改性，并接枝了交联的胶原蛋白。胶原的交联剂是戊二醛。研究了戊二醛浓度，交联时间和交联温度对膜性能和表面结构的影响。通过接触角和纯净水通量表征了改性膜的性能。用偏光显微镜观察用酸性染料染色的膜的表面结构。改性膜的特征在于渗透性和吸附能力。牛血清白蛋白（BSA）用作模型蛋白。通过甲基噻唑基四唑鎓（MTT）方法检查膜的细胞培养能力。当胶原蛋白与0.4 wt％戊二醛在35℃下交联1 h时，膜表面上的胶原蛋白接枝量达到最大。BSA吸附能力和细胞培养能力测试表明，交联的PVDF膜胶原具有良好的亲水性和生物相容性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号