Bauhinia Kunitz-type proteinase inhibitors: structural characteristics and biological properties.

Vilela-Oliva ML; Sampaio MU

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Bauhinia Kunitz-type proteinase inhibitors: structural characteristics and biological properties.

机译：紫荆花Kunitz型蛋白酶抑制剂：结构特征和生物学特性。

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Abstract Plant proteinase inhibitors are involved in the regulation of the activity of many proteinases and, in consequence, in biological processes driven by proteolysis. In this review, we summarize recent results on the activity of native Bauhinia inhibitors and synthetic derivatives. Structural and functional characteristics and the potential therapeutic use of these inhibitors are also discussed.

机译：摘要植物蛋白酶抑制剂参与了许多蛋白酶活性的调节，并因此参与了由蛋白水解驱动的生物过程。在这篇综述中，我们总结了有关天然紫荆花抑制剂和合成衍生物活性的最新结果。还讨论了这些抑制剂的结构和功能特征以及潜在的治疗用途。

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《Biological chemistry》 |2008年第8期|共7页
作者
Vilela-Oliva ML; Sampaio MU;
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正文语种 eng
中图分类生物化学;
关键词
inhibitors; Endopeptidases; proteolysis; Review Publication Type; derivatives;

机译：抑制剂;内肽酶;蛋白水解;综述[出版物类型];衍生物;

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专利

1. Bauhinia Kunitz-type proteinase inhibitors: structural characteristics and biological properties. [J] . Vilela-Oliva ML, Sampaio MU Biological chemistry . 2008,第8期

机译：紫荆花Kunitz型蛋白酶抑制剂：结构特征和生物学特性。
2. Kunitz-type Bauhinia bauhinioides inhibitors devoid of disulfide bridges: isolation of the cDNAs, heterologous expression and structural studies [J] . Araujo APU, Hansen D, Vieira DF, Biological chemistry . 2005,第6期

机译：不含二硫键的Kunitz型紫荆花紫荆抑制剂：cDNA的分离，异源表达和结构研究
3. Aryl-substituted methyleneaminoxymethyl (MAOM) analogues of diarylcyclopentenyl cyclooxygenase-2 inhibitors: effects of some structural modifications on their biological properties. [J] . Balsamo A, Coletta I, Guglielmotti A, European Journal of Medicinal Chemistry: Chimie Therapeutique . 2002,第7期

机译：二芳基环戊烯基环氧合酶-2抑制剂的芳基取代的亚甲基氨基氧甲基（MAOM）类似物：一些结构修饰对其生物学特性的影响。
4. A NEW FAMILY OF SERINE PROTEINASE INHIBITORS: PURIFICATION, AMINO ACID SEQUENCE, TOPOLOGY OF DISULFIDE BRIDGES AND CHEMICAL SYNTHESIS OF INHIBITORS ISOLATED FROM Mirabilis jalapa AND Spinacia oleracea SEEDS [C] . Joanna Kowalska, Anna Wilimowska-Pelc, Izabela Lorenc-Kubis the European Peptide Symposium . 2007

机译：一种新的丝氨酸蛋白酶抑制剂系列：纯化，氨基酸序列，二硫化物桥的拓扑，抑制剂的化学合成从Mirabilis jalapa和Spinacia Oleracea种子中分离出来
5. A comparative analysis of the FIXa active site using Kunitz-type inhibitors. [D] . Williamson, Stephen Robert. 2005

机译：使用Kunitz型抑制剂对FIXa活性位点的比较分析。
6. Isolation Cloning and Structural Characterisation of Boophilin a Multifunctional Kunitz-Type Proteinase Inhibitor from the Cattle Tick [O] . Sandra Macedo-Ribeiro, Carla Almeida, Bárbara M. Calisto, 2008

机译：牛ick的多功能Kunitz型蛋白酶抑制剂Boophilin的分离克隆和结构表征
7. Isolation, cloning and structural characterisation of boophilin, a multifunctional kunitz-type proteinase inhibitor from the cattle tick [O] . Macedo-Ribeiro, Sandra, Almeida, Carla, Calisto, Barbara M., 2008

机译：牛tick中的多功能kunitz型蛋白酶抑制剂Boophilin的分离，克隆和结构表征
8. Human Kunitz-Type Inhibitor with Enhanced Antifibrinolytic Activity. [R] . Kisiel, W., Chand, H. S. 2005

机译：人类Kunitz型抑制剂具有增强的抗纤维蛋白溶解活性。

Bauhinia Kunitz-type proteinase inhibitors: structural characteristics and biological properties.

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