• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>RSC Advances >Self-assembly of monolayered lipid membranes for surface-coating of a nanoconfined Bombyx mori silk fibroin film
【24h】

Self-assembly of monolayered lipid membranes for surface-coating of a nanoconfined Bombyx mori silk fibroin film

机译：单层脂质膜的自组装，用于纳米约束家蚕丝素蛋白膜的表面涂层

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Regenerated Bombyx mori (B. mori) silk fibroin is a type of widely used biomaterial. The beta-sheet structure of it after methanol treatment provides water-insolubility and mechanical stability while on the other side leads to a hydrophobic surface which is less preferred by biological systems. In this work we prepare a novel type of nanoconfined silk fibroin film with a thickness below 100 nm. The film has a flat while hydrophobic surface because of its beta-sheet structure due to the z-direction confinement during formation. Different types of lipid monolayers, DOPC, DPPC and MO, are assembled on the silk film surface. The lipid coating, especially the DPPC membrane, provides a much smoother and more hydrophilic surface due to the gel phase tails of the lipids, in comparison with the DOPC and MO ones which are in a liquid phase and have a much stronger interfacial association between silk film surface and lipid tails. Such a lipid coating preserves the biocompatibility and cellular affinity of the silk film which promises potential applications as surface coatings for materials for biological use.
机译：再生家蚕（B. mori）丝素蛋白是一种广泛使用的生物材料。甲醇处理后的β-折叠结构提供了水不溶性和机械稳定性，而另一方面导致了疏水性表面，这是生物系统所不希望的。在这项工作中，我们准备了一种新型的纳米约束丝素蛋白膜，其厚度低于100 nm。该膜具有平坦而疏水的表面，这是因为在形成过程中由于z方向的限制，它具有β-折叠结构。在丝膜表面上组装了不同类型的脂质单层，即DOPC，DPPC和MO。由于脂质的凝胶相尾，与液相中的DOPC和MO相比，脂质涂层（尤其是DPPC膜）提供了更加平滑和亲水的表面，而DOPC和MO处于液相中并且在丝之间具有更强的界面缔合膜表面和脂质尾巴。这种脂质涂层保留了丝膜的生物相容性和细胞亲和力，从而有望作为生物材料用表面涂层的潜在应用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号