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首页> 外文期刊>Rheumatology >A simple extension to the Rheumatoid Arthritis Quality of Life Questionnaire (RAQol) to explore individual patient concerns and monitor group outcome in clinical practice.
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A simple extension to the Rheumatoid Arthritis Quality of Life Questionnaire (RAQol) to explore individual patient concerns and monitor group outcome in clinical practice.

机译：类风湿关节炎生活质量调查表（RAQol）的简单扩展，可探讨患者的个人担忧并在临床实践中监测小组的结果。

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OBJECTIVES: To find out if the RAQol, if extended by a qualifying question on the level of concern associated with each item, can function both as a group outcome measure and as a useful tool to identify the concerns of individual patients. METHODS: Thirty-seven rheumatoid arthritis (RA) patients completed the questionnaire before and after starting a biological therapy. One hundred and forty-five others receiving routine care completed it at baseline, weeks 12 and 13 with EuroQol VAS and questions on global arthritis impact and any other concerns. Reproducibility was assessed in all 59 participants whose condition remained stable between weeks 12 and 13. RESULTS: The RAQol score was highly reproducible (intraclass correlation coefficient 0.986, n=59), reflected global RA impact (P = 0.000, n=140), negatively correlated with EuroQol VAS (Spearman coefficient=-0.639, two-tailed significance=0.000, n=142), responsive to biological therapy (two-tailed P= 0.000) and to increased global RA impact over 12 weeks (two-tailed P=0.012, n=37), and had high internal consistency (Cronbach's alpha=0.94, n=143). The number of issues of great concern and their percentage contribution to the RAQol score were related to global arthritis impact (P=0.000 for both) and reduced by a biological therapy (two-tailed P=0.000 and 0.001 respectively). The mean kappa for consistency in identifying each item as a concern was 0.801 (range 0.633-0.921). CONCLUSIONS: Use of the 'extended' RAQol in clinical practice could provide a valid and sensitive score for monitoring group outcome and a comprehensive and consistent list of an individual's main issues of concern to assist assessment of needs in routine clinical practice.
机译：目的：找出RAQol，如果在与每个项目相关的关注水平上通过限定性问题进行扩展，是否既可以作为小组结果衡量指标，又可以作为识别单个患者关注问题的有用工具。方法：37名类风湿关节炎（RA）患者在开始生物治疗之前和之后完成了调查问卷。 145名接受常规护理的人员在基线，第12周和第13周使用EuroQol VAS完成了该护理，并就全球关节炎的影响和其他任何问题提出了疑问。在所有第12周到第13周之间保持稳定的59位参与者中评估了可重复性。结果：RAQol评分具有高度可重复性（类内相关系数0.986，n = 59），反映了总体RA影响（P = 0.000，n = 140），与EuroQol VAS呈负相关（Spearman系数= -0.639，两尾显着性= 0.000，n = 142），对生物治疗有反应（两尾P = 0.000），并在12周内对全球RA影响增加（两尾P = 0.012，n = 37），并且具有很高的内部一致性（Cronbach's alpha = 0.94，n = 143）。引起高度关注的问题数量及其对RAQol评分的贡献率与总体关节炎影响有关（两者均P均0.000），并通过生物疗法得以减少（两尾P分别为0.000和0.001）。将每个项目识别为关注点时的一致性的平均kappa为0.801（范围0.633-0.921）。结论：在临床实践中使用“扩展的” RAQol可提供有效且敏感的评分，以监测小组的结果，并提供个人主要关注问题的全面一致的清单，以帮助评估常规临床实践中的需求。

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