Developments in glucocorticoid therapy.

Bijlsma JW; Saag KG; Buttgereit F; da Silva JA

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Developments in glucocorticoid therapy.

机译：糖皮质激素治疗的发展。

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Recent evidence for a disease-modifying potential of low-dose glucocorticoids (GCs) in the treatment of rheumatoid arthritis has renewed the debate on the risk benefit ratio with this therapy. Two recent developments are described that might have a positive influence on these risk benefit ratios. One is the improvement in new GC compounds--designer GCs, alterations in bioactivity, and alterations in formulations. The other is a better understanding and management of the toxicity of GCs.

机译：低剂量糖皮质激素（GCs）在类风湿关节炎治疗中具有潜在的疾病改良潜力的最新证据重新引发了对该疗法风险收益比的争论。描述了两个最新发展，这些发展可能会对这些风险收益率产生积极影响。一种是新型气相色谱化合物的改进-设计气相色谱仪，生物活性的改变和配方的改变。另一个是对GC毒性的更好理解和管理。

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来源
《Rheumatic diseases clinics of North America》 |2005年第1期|共18页
作者
Bijlsma JW; Saag KG; Buttgereit F; da Silva JA;
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正文语种 eng
中图分类内科学;
关键词
Therapeutic procedure; Glucocorticoids; treatment risk-benefit analysis; 糖皮质激素类;

机译：Therapeutic procedure;Glucocorticoids;treatment risk-benefit analysis;糖皮质激素类;

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1. Developments in glucocorticoid therapy. [J] . Bijlsma JW, Saag KG, Buttgereit F, Rheumatic diseases clinics of North America . 2005,第1期

机译：糖皮质激素治疗的发展。
2. Impact of glucocorticoid-induced adverse events on adherence in patients receiving long-term systemic glucocorticoid therapy. [J] . Arena C, Morin AS, Blanchon T, British Journal of Dermatology . 2010,第4期

机译：接受长期全身糖皮质激素治疗的患者中糖皮质激素引起的不良事件对依从性的影响。
3. Glucocorticoid-induced granzyme A expression can be used as a marker of glucocorticoid sensitivity for acute lymphoblastic leukemia therapy. [J] . Myoumoto A, Nakatani K, Koshimizu TA, Journal of human genetics . 2007,第4期

机译：糖皮质激素诱导的粒酶A表达可用作急性淋巴细胞白血病治疗中糖皮质激素敏感性的标志物。
4. Development of plasmonic aluminum structures with high chemical stability and their application for photothermal therapy. [C] . Jotaro Honda, Miu Danno, Kosuke Sugawa 日本化学会春季年会講演予稿集 . 2018

机译：具有高化学稳定性的等离子体铝结构及其对光热疗法的应用。
5. Developmental Misprogramming of Metabolism by Endocrine-Disrupting Chemicals: A Focus on the Glucocorticoid Receptor-Modulating Fungicide Tolylfluanid [D] . Ruiz, Daniel. 2019

机译：内分泌破坏化学品的新陈代谢的发育误导性：对糖皮质激素受体调节杀菌剂毒溶细胞的关注
6. Bone protection in chronic obstructive pulmonary disease (COPD) patients requiring regular intermittent glucocorticoid therapy. [O] . Kavitha Nadesalingam, David Kirby 2013

机译：需要定期间歇糖皮质激素治疗的慢性阻塞性肺疾病（COPD）患者的骨骼保护。
7. A retrospective observational study of glucocorticoid-induced diabetes mellitus with IgA nephropathy treated with tonsillectomy plus methylprednisolone pulse therapy. [O] . Yoshia Miyawaki, Takayuki Katsuyama, Ken-Ei Sada, 2017

机译：用扁桃体切除加甲基强的松龙冲击疗法治疗糖皮质激素诱导的糖尿病合并Iga肾病的回顾性观察研究。

Developments in glucocorticoid therapy.

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