Estrogen-induced expression of tumor necrosis factor-like weak inducer of apoptosis through ER alpha accelerates the progression of lupus nephritis

Xue Leixi; Liu Zhiqin; Hu Ji; Huang Jun; Wen Jian; Liu Zhichun

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Estrogen-induced expression of tumor necrosis factor-like weak inducer of apoptosis through ER alpha accelerates the progression of lupus nephritis

机译：雌激素诱导的ERα表达的肿瘤坏死因子样弱凋亡诱导剂加速狼疮性肾炎的进展

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Objectives. Oestrogens have been shown to play key roles in the pathogenesis of SLE. The aim of this study was to investigate the roles and mechanisms of 17 beta-estradiol (E2) in TNF-like weak inducer of apoptosis (TWEAK) expression in LN.

机译：目标。雌激素已显示在SLE的发病机理中起关键作用。这项研究的目的是研究17β-雌二醇（E2）在LN中的TNF样细胞凋亡弱诱导剂（TWEAK）表达中的作用和机制。

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《Rheumatology》 |2016年第10期|共9页
作者
Xue Leixi; Liu Zhiqin; Hu Ji; Huang Jun; Wen Jian; Liu Zhichun;
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正文语种 eng
中图分类免疫性疾病;
关键词
systemic lupus erythematosus (SLE); tumor necrosis factor-like weak inducer of apoptosis (TWEAK); 17 beta-estradiol (E2); estrogen receptor alpha (ER alpha);

机译：系统性红斑狼疮（SLE）;肿瘤坏死因子样凋亡的弱诱导剂（TWEAK）;17β-雌二醇（E2）;雌激素受体α（ER alpha）;

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专利

1. Estrogen-induced expression of tumor necrosis factor-like weak inducer of apoptosis through ER alpha accelerates the progression of lupus nephritis [J] . Xue Leixi, Liu Zhiqin, Hu Ji, Rheumatology . 2016,第10期

机译：雌激素诱导的ERα表达的肿瘤坏死因子样弱凋亡诱导剂加速狼疮性肾炎的进展
2. Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Accelerates the Progression of Renal Fibrosis in Lupus Nephritis by Activating SMAD and p38 MAPK in TGF-beta 1 Signaling Pathway [J] . Liu Zhiqin, Xue Leixi, Liu Zhichun, Mediators of inflammation . 2016,第Pta3期

机译：肿瘤坏死因子弱凋亡器凋亡器通过在TGF-Beta 1信号通路中激活Smad和P38 MAPK来加速狼疮肾炎中肾纤维化的进展
3. Elevation of human tumor necrosis factor-like weak inducer of apoptosis in peripheral blood mononuclear cells is correlated with disease activity and lupus nephritis in patients with systemic lupus erythematosus. [J] . Liu ZC, Zhou QL, Li XZ, Cytokine . 2011,第3期

机译：系统性红斑狼疮患者外周血单个核细胞中人肿瘤坏死因子样弱凋亡诱导剂的升高与疾病活动和狼疮性肾炎有关。
4. Role of Sphingosine Kinase in the Expression of Adhesion Molecules on Monocytes Induced by Tumor Necrosis Factor-Alpha (Relevant to Atherosclerosis) [C] . Tuang Chew Yan, Zhong Liang, Alirio, . 2005

机译：鞘氨醇激酶在肿瘤坏死因子-α（与动脉粥样硬化有关）诱导的单核细胞粘附分子表达中的作用
5. Mechanisms of hepatocellular apoptosis induced by trovafloxacin-tumor necrosis factor-alpha interaction: An in vitro model of idiosyncratic drug-induced liver injury. [D] . Beggs, Kevin Michael. 2013

机译：曲伐沙星-肿瘤坏死因子-α相互作用诱导的肝细胞凋亡机制：特异药物诱导的肝损伤的体外模型。
6. Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Accelerates the Progression of Renal Fibrosis in Lupus Nephritis by Activating SMAD and p38 MAPK in TGF-β1 Signaling Pathway [O] . Zhiqin Liu, Leixi Xue, Zhichun Liu, 2016

机译：肿瘤坏死因子样凋亡诱导剂通过激活TGF-β1信号通路中的SMAD和p38 MAPK促进狼疮性肾炎肾纤维化的进展
7. Estrogen-induced expression of tumor necrosis factor-like weak inducer of apoptosis through ERα accelerates the progression of lupus nephritis [O] . Leixi Xue, Zhiqin Liu, Ji Hu, 2016

机译：雌激素诱导的肿瘤坏死因子弱诱导剂的表达通过Erα加速了狼疮性肾炎的进展
8. IL-1 and Tumor Necrosis Factor-Alpha Each Up-Regulate Both the Expression of IFN-Gamma Receptors and Enhance IFN-Gamma-Induced HLA-DR Expression on Human Monocytes and a Human Monocytic Cell Line (THP-1) [R] . Krakauer, T., Oppenheim, J. J. 1993

机译：IL-1和肿瘤坏死因子-α各自上调IFN-γ受体的表达并增强人单核细胞和人单核细胞系（THp-1）上IFN-γ诱导的HLa-DR表达

Estrogen-induced expression of tumor necrosis factor-like weak inducer of apoptosis through ER alpha accelerates the progression of lupus nephritis

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