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Facile synthesis of novel size-controlled antibacterial hybrid spheres using silver nanoparticles loaded with poly-dopamine spheres

机译:使用载有聚多巴胺球的银纳米粒子轻松合成新型的尺寸可控的抗菌杂化球

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摘要

Silver nanoparticles have been proven to exhibit excellent antimicrobial activity, but problems such as aggregation and toxicity limit their practical application. To solve these problems, a kind of sub-micrometer poly-dopamine spheres loaded with silver nanoparticles (Ag@PDS) were fabricated using a facile method. Silver nitrate was reduced by poly-dopamine spheres (PDS) without surface modification, and no other reducing agent added. This entire preparation process is very green, simple and efficient. As a result, Ag NPs have been fixed and uniformly dispersed onto the surface of the PDS, which can effectively prevent Ag NPs from aggregating or oxidizing during their application. Because the size of the uniform hybrid sphere is easily controlled by adjusting the ratio of ammonia to dopamine, it is convenient to fabricate hybrid spheres with desired sizes. These hybrids are capable of completely inhibiting bacterial growth because of their excellent antibacterial properties. Finally, the prospect of the organismal level impact of the Ag@PDS hybrid has also been proposed.
机译:银纳米颗粒已被证明具有优异的抗菌活性,但是诸如聚集和毒性的问题限制了它们的实际应用。为了解决这些问题,采用一种简便的方法制备了一种载有银纳米颗粒的亚微米级聚多巴胺球(Ag @ PDS)。硝酸银可通过聚多巴胺球(PDS)还原而无需表面改性,也无需添加其他还原剂。整个准备过程非常绿色,简单而高效。结果,Ag NP被固定并均匀地分散在PDS的表面上,这可以有效地防止Ag NP在其应用过程中聚集或氧化。由于通过调节氨与多巴胺的比例可以容易地控制均匀的混合球的尺寸,因此方便地制造具有期望尺寸的混合球。这些杂种具有出色的抗菌性能,因此能够完全抑制细菌的生长。最后,还提出了Ag @ PDS杂种对生物体水平的影响的前景。

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