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Antibody nanosensors: a detailed review

机译:抗体纳米传感器:详细评论

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In this review, the authors will discuss novel and prospective antibody nanosensors for the detection of specific analytes used in a number of fields of analytical chemistry. Biosensors-transducers that incorporate biological molecules for recognition-have been found to be fundamental in a number of chemical, clinical, and environmental analyses. Antibody nanosensors make up a large area of this research, as the antibodies' specific recognition elements make them highly selective and sensitive. These biological molecules can also be tailored to recognize any single analyte or group of analytes, and can be easily functionalized to a number of nanomaterial substrates. Herein, a number of antibody nanosensor transduction methods will be examined, including electrochemical, optical, magnetic, and piezoelectric, among others that fall into multiple categories. This review will show that it is clear that antibody nanosensors-and nanosensors in general-are highly sensitive no matter the transduction method, and that various transduction methods can be suited for a number of different applications.
机译:在这篇综述中,作者将讨论用于检测在分析化学领域中使用的特定分析物的新型和前瞻性抗体纳米传感器。已经发现,结合了生物分子以进行识别的生物传感器-换能器是许多化学,临床和环境分析的基础。抗体纳米传感器构成了这项研究的主要领域,因为抗体的特异性识别元件使其具有高度的选择性和敏感性。还可以定制这些生物分子以识别任何单个分析物或一组分析物,并且可以轻松地使其功能化为多种纳米材料基质。在本文中,将检查多种抗体纳米传感器转导方法,包括电化学,光学,磁性和压电等,这些方法属于多种类别。这项审查将表明,很明显,无论转导方法如何,抗体纳米传感器(以及一般而言的纳米传感器)都是高度敏感的,并且各种转导方法都可以适用于许多不同的应用。

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