A colorimetric and ratiometric fluorescent pH probe based on ring opening/closing approach and its applications in monitoring cellular pH change

You Qi-Hua; Lee Yee Man; Chan Wing Hong; Mak Nai Ki; Lee Albert W. M.; Hau Sam C. K.; Mak Thomas C. W.

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A colorimetric and ratiometric fluorescent pH probe based on ring opening/closing approach and its applications in monitoring cellular pH change

机译：基于开环/闭环方法的比色和比例荧光pH探针及其在监测细胞pH变化中的应用

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摘要

A colorimetric and ratiometric fluorescent pH probe with a pK(a) value of 6.0 based on a ring opening/closing approach of N,O-disubstituted hemiaminal ether has been developed. The probe exhibits fast response toward pH change with high selectivity and low cytotoxicity and was applied in HK-1 cells to visualize pH change.

机译：基于N，O-二取代的半缩醛醚的开环方法，pK（a）值为6.0的比色和比例荧光pH探针已经开发出来。该探针显示出对pH变化的快速响应，具有高选择性和低细胞毒性，并应用于HK-1细胞以观察pH变化。

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《RSC Advances》 |2015年第6期|共4页
作者
You Qi-Hua; Lee Yee Man; Chan Wing Hong; Mak Nai Ki; Lee Albert W. M.; Hau Sam C. K.; Mak Thomas C. W.;
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正文语种 eng
中图分类化学;
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1. A colorimetric and ratiometric fluorescent pH probe based on ring opening/closing approach and its applications in monitoring cellular pH change [J] . You Qi-Hua, Lee Yee Man, Chan Wing Hong, RSC Advances . 2015,第6期

机译：基于开环/闭环方法的比色和比例荧光pH探针及其在监测细胞pH变化中的应用
2. A novel ratiometric and colorimetric fluorescent probe for hypochlorite based on cyanobiphenyl and its applications [J] . Tang Xu, Zhu Zhi, Liu Renjie, Spectrochimica acta, Part A. Molecular and biomolecular spectroscopy . 2019,第期

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3. A highly sensitive colorimetric and ratiometric fluorescent probe based on 3-hydroxyphthalimide for detection of Hg2+ in aqueous solution and its application in real sample analysis [J] . Yang Binying, Huang Jing, Bao Cheng, Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 2020,第9期

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4. Optical carbon dioxide sensor based on the colorimetric change of a-naphtholphthalein and internal reference fluorescent CIS/ZnS QDs [C] . Cheng-Shane Chu, Meng-Wei Hsieh International conference on optical fiber sensors . 2017

机译：基于α-萘酞菁比色变化和内部参考荧光CIS / ZnS QD的光学二氧化碳传感器
5. Ratiometric Near-Infrared Fluorescent Probes for the Sensitive Detection of Intracellular pH and Bio-Thiols in Live Cells [D] . Xia, Shuai . 2020

机译：大率近红外荧光荧光探针，用于活细胞中细胞内pH和生物硫醇的敏感性检测
6. Ratiometric Near-Infrared Fluorescent Probes Based On Through-Bond Energy Transfer and π-Conjugation Modulation between Tetraphenylethene and Hemicyanine Moieties for Sensitive Detection of pH Changes in Live Cells [O] . Jianbo Wang, Shuai Xia, Jianheng Bi, -1

机译：基于四苯乙烯和半菁部分之间的键间能量转移和π共轭调制的比率式近红外荧光探针用于灵敏检测活细胞的pH变化
7. A colorimetric and ratiometric fluorescent pH probe based on ring opening/closing approach and its applications in monitoring cellular pH change [O] . Qi-Hua You, Yee Man Lee, Wing Hong Chan, 2015

机译：基于环形开启/关闭方法的比色和比例荧光pH探针及其在监测细胞pH变化中的应用

A colorimetric and ratiometric fluorescent pH probe based on ring opening/closing approach and its applications in monitoring cellular pH change

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