Non-covalent functionalization of carbon nano-onions with pyrene-BODIPY dyads for biological imaging

Bartelmess Juergen; Frasconi Marco; Balakrishnan Preethi B.; Signorelli Angelo; Echegoyen Luis; Pellegrino Teresa; Giordani Silvia

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Non-covalent functionalization of carbon nano-onions with pyrene-BODIPY dyads for biological imaging

机译：碳纳米离子与pyr-BODIPY二元化合物的非共价官能化，用于生物成像

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We report a novel approach based on non-covalent interactions for the functionalization of carbon nano-onions (CNOs) with fluorophores. The assembly of pyrene-BODIPY conjugates on the CNO surface by means of pi-pi-stacking results in fluorescent carbon nanoparticles that are successfully uptaken by HeLa cancer cells with no cytotoxicity observed. The ability to functionalize carbon-based nanomaterials by using mild conditions will pave the way for future clinical application of these versatile nanomaterials.

机译：我们报告了一种基于非共价相互作用的新型方法，具有荧光团的碳纳米洋葱（CNOs）的功能化。 -BODIPY偶联物通过pi-pi堆积在CNO表面的组装导致荧光碳纳米颗粒被HeLa癌细胞成功摄取，而未观察到细胞毒性。通过使用温和条件使碳基纳米材料功能化的能力将为这些通用纳米材料的未来临床应用铺平道路。

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《RSC Advances》 |2015年第62期|共6页
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Bartelmess Juergen; Frasconi Marco; Balakrishnan Preethi B.; Signorelli Angelo; Echegoyen Luis; Pellegrino Teresa; Giordani Silvia;
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中图分类化学;
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1. Non-covalent functionalization of carbon nano-onions with pyrene-BODIPY dyads for biological imaging [J] . Bartelmess Juergen, Frasconi Marco, Balakrishnan Preethi B., RSC Advances . 2015,第62期

机译：碳纳米离子与pyr-BODIPY二元化合物的非共价官能化，用于生物成像
2. Tracing chirality, diameter dependence, and temperature-controlling of single-walled carbon nanotube non-covalent functionalization by biologically compatible peptide: insights from molecular dynamics simulations [J] . Tohidifar Leila, Hadipour Nasser L. Journal of molecular modeling . 2019,第9期

机译：通过生物相容肽的单壁碳纳米管非共价官能化的跟踪性儿，直径依赖性和温度控制：来自分子动力学模拟的见解
3. A one-step ultrasonic irradiation assisted strategy for the preparation of polymer-functionalized carbon quantum dots and their biological imaging [J] . Huang Hongye, Cui Yi, Liu Meiying, Journal of Colloid and Interface Science . 2018,第期

机译：一种一步式超声辐射辅助策略，用于制备聚合物官能化碳量子点及其生物成像
4. FUNCTIONALIZED CARBON NANO-ONIONS AS IMAGING PROBES FOR CANCER CELLS [C] . Silvia Giordani, Marco Frasconi, Roberto Marotta World Conference on Carbon . 2016

机译：官能化碳纳米洋葱作为癌细胞的成像探针
5. Functionalization of carbon nanotubes for polymeric carbon nanocomposites and biological conjugates. [D] . Lin, Yi. 2004

机译：碳纳米管的功能化，用于聚合碳纳米复合材料和生物共轭物。
6. Design of Novel Pyrene-Bodipy Dyads: Synthesis Characterization Optical Properties and FRET Studies [O] . Pasquale Porcu, Mireille Vonlanthen, Israel González-Méndez, 2018

机译：新型P双联二元体的设计：合成表征光学性质和FRET研究。
7. Non-covalent functionalization of carbon nano-onions with pyrene–BODIPY dyads for biological imaging [O] . Juergen Bartelmess, Marco Frasconi, Preethi B. Balakrishnan, 2015

机译：与生物成像芘 - Bodipy Dyads的碳纳米洋葱的非共价官能化

Non-covalent functionalization of carbon nano-onions with pyrene-BODIPY dyads for biological imaging

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