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Microwave-assisted C-N and C-S bond-forming reactions: an efficient three-component domino sequence for the synthesis of sulfoether-decorated imidazo[1,2-a]pyridines

机译:微波辅助的C-N和C-S键形成反应:合成硫醚修饰的咪唑并[1,2-a]吡啶的有效三组分多米诺序列

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摘要

An efficient and simple microwave-assisted three-component reaction for the formation of imidazo[1,2-a] pyridine derivatives in the presence of F3CCO2H has been described. The three-component reaction of 3-phenylpropiolaldehyde, pyridin-2-amines and thiols gives the desired products in good yields. It represents an efficient approach for the formation of C-N and C-S bonds under microwave irradiation.
机译:已经描述了在F 3 CCO 2 H存在下形成咪唑并[1,2-a]吡啶衍生物的有效且简单的微波辅助三组分反应。 3-苯基丙醛,吡啶-2-胺和硫醇的三组分反应以高收率得到所需产物。它代表了在微波辐射下形成C-N和C-S键的有效方法。

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