Asymmetric synthesis towards doxanthrine, a dopamine D1 full agonist

Malhotra Rajesh; Ghosh Amit; Dutta Swarup; Dey Tushar K.; Basu Sourav; Hajra Saumen

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Asymmetric synthesis towards doxanthrine, a dopamine D1 full agonist

机译：多巴胺D1全激动剂多黄嘌呤的不对称合成

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Asymmetric synthesis of O-methyl doxanthrine is accomplished with high diastereo- and enantioselectivity from beta-aryloxyamino acid derived from D-serine.

机译：O-甲基多黄嘌呤的不对称合成是由衍生自D-丝氨酸的β-芳氧基氨基酸以高非对映选择性和对映选择性完成的。

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《RSC Advances》 |2014年第89期|共4页
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Malhotra Rajesh; Ghosh Amit; Dutta Swarup; Dey Tushar K.; Basu Sourav; Hajra Saumen;
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正文语种 eng
中图分类化学;
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1. Asymmetric synthesis towards doxanthrine, a dopamine D1 full agonist [J] . Malhotra Rajesh, Ghosh Amit, Dutta Swarup, RSC Advances . 2014,第89期

机译：多巴胺D1全激动剂多黄嘌呤的不对称合成
2. Construction of Arene-Fused-Piperidine Motifs by Asymmetric Addition of 2-Trityloxymethylaryllithiums to Nitroalkenes: The Asymmetric Synthesis of a Dopamine D1 Full Agonist, A-86929 [J] . Mitsuaki Yamashita, Ken-ichi Yamada, Kiyoshi Tomioka Journal of the American Chemical Society . 2004,第7期

机译：通过不对称加成2-三苯甲基甲氧基甲基芳基锂到硝基烯烃的芳烃融合的哌啶基序的构建：多巴胺D1完全激动剂A-86929的不对称合成
3. Improved asymmetric synthesis of dopamine D1 full agonist, dihydrexidine, employing chiral ligand-controlled asymmetric conjugate addition of aryllithium to a nitroalkene [J] . Yamashita M, Yamada KI, Tomioka K Tetrahedron . 2004,第19期

机译：使用手性配体控制的芳基锂与硝基烯烃的不对称共轭加成反应，改善多巴胺D1全激动剂二氢己定的不对称合成
4. l-stepholidine, a naturally occurring dopamine D1 receptor agonist and D2 receptor antagonist, attenuates methamphetamine self-administration in rate [C] . Kai Yue, BaoMiao Ma, JunQiao Xing International Conference on Applied Sciences, Engineering and Technology . 2014

机译：L- StepHolidine，天然存在的多巴胺D1受体激动剂和D2受体拮抗剂，衰减甲基苯丙胺自我管理
5. PART 1: SYNTHESIS OF IRREVERSIBLE INHIBITORS OF ALDOSE REDUCTASE WITH SUBSEQUENT DEVELOPMENT OF A CARBON-13 NMR PROTEIN PROBE. PART 2: SYNTHESIS OF SELENIUM ANALOGS OF DOPAMINE AS POTENTIAL DOPAMINE RECEPTOR AGONISTS. [D] . ARES, JEFFREY JOSEPH. 1986

机译：第1部分：合成具有碳13 NMR蛋白质探针的醛糖还原酶的不可逆抑制剂。第2部分：作为潜在的多巴胺受体激动剂的多巴胺硒类似物的合成。
6. Comparison of the enantiomers of (±)-doxanthrine a high efficacy full dopamine D1 receptor agonist and a reversal of enantioselectivity at D1 versus alpha2C adrenergic receptors [O] . Julie A. Przybyla, Juan P. Cueva, Benjamin R. Chemel, -1

机译：高效全多巴胺D1受体激动剂（±）-地黄嘌呤的对映异构体的比较以及D1与α2C肾上腺素能受体的对映选择性逆转
7. Comparison of the enantiomers of (±)-doxanthrine, a high efficacy full dopamine D1 receptor agonist, and a reversal of enantioselectivity at D1 versus alpha2C adrenergic receptors [O] . Przybyla, Julie A., Cueva, Juan P., Chemel, Benjamin R., 2009

机译：高效全多巴胺D1受体激动剂（±）-地黄嘌呤的对映异构体的比较，以及D1与α2C肾上腺素能受体的对映选择性逆转
8. Comparison of the D1-Dopamine Agonists SKF-38393 and A-68930 in Neonatal 6-Hydroxydopamine-Lesioned Rats: Behavioral Effects and Industion of c-fos-Like Immunoreactivity. [R] . Johnson, K. B., Criwell, H. E., Jensen, K. F., 1992

机译：D1-多巴胺激动剂sKF-38393和a-68930在新生儿6-羟基多巴胺损伤大鼠中的比较：行为效应和c-fos样免疫反应性的产生。

Asymmetric synthesis towards doxanthrine, a dopamine D1 full agonist

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