• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>RSC Advances >Parmeliaceae family: phytochemistry, pharmacological potential and phylogenetic features
【24h】

Parmeliaceae family: phytochemistry, pharmacological potential and phylogenetic features

机译：伞形科：植物化学，药理潜力和系统发育特征

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Parmeliaceae is the largest family of lichenized fungi comprising about 2700 species distributed in about 80 genera. A wide array of secondary metabolites including depsides, depsidones, aliphatic acids, triterpenes, anthraquinones, secalonic acids, pulvinic acid derivatives and xanthones have been identified within this family. Many of these bioactive compounds such as usnic acid and atranorin are exclusively found in this family, being of great relevance for the systematics and phylogeny. Moreover, these compounds exert different biological roles including antimicrobial, antioxidant, cytotoxic, anti-inflammatory, analgesic and enzyme inhibitory actions. The current review focuses on the phytochemistry and main phylogenetic aspects of Parmeliaceae, and it discusses the pharmacological findings and mechanisms of action of their extracts and isolated compounds. The present work actually collects information related to more than 65 lichen species (from 21 different genuses and heterogeneous distribution) and 75 isolated metabolites. As reported, the best studied genus from a pharmacological point of view is Parmelia, followed by Usnea. At the species level, Cetraria islandica and Evernia prunastri attract remarkable interest in their bioactive activities and metabolite content. The major pharmacological activities investigated on extracts and compounds from Parmeliaceae spp. have been antimicrobial, anticancer and antioxidant potentials; and regarding isolated compounds, the aforementioned usnic acid and atranorin are among the most studied metabolites. Reviewed data suggest that some of these lichens and natural compounds are worthy of further investigation.
机译：虎杖科是最大的地衣真菌家族，包括分布在约80属中的约2700种。在该家族中已鉴定出许多次级代谢产物，包括de苷，二烯哌啶酮，脂族酸，三萜烯，蒽醌，secalonic酸，pulvinic酸衍生物和氧杂蒽酮。这些生物活性化合物中的许多，例如松萝酸和阿特拉诺林，都是在该家族中唯一发现的，与系统学和系统发育关系密切。而且，这些化合物发挥不同的生物学作用，包括抗微生物，抗氧化剂，细胞毒性，抗炎，止痛和酶抑制作用。目前的审查侧重于虎耳草科的植物化学和主要的系统发育方面，并讨论了其提取物和分离的化合物的药理学发现和作用机理。目前的工作实际上收集了与65种以上地衣物种有关的信息（来自21种不同的属和异质分布）和75种分离的代谢产物。如所报道的，从药理学角度来看，研究最好的属是Parmelia，其次是Usnea。在物种层面上，Cetraria islandica和Evernia prunastri对它们的生物活性和代谢物含量引起了极大的兴趣。研究了对虎耳草科植物提取物和化合物的主要药理活性。具有抗菌，抗癌和抗氧化的潜力;对于分离的化合物，上述松萝酸和阿特拉诺林是研究最多的代谢产物。审查的数据表明，其中一些地衣和天然化合物值得进一步研究。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号