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Glucose detection using SERS with multi-branched gold nanostructures in aqueous medium

机译:在水性介质中使用具有多分支金纳米结构的SERS进行葡萄糖检测

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摘要

Gold nanoparticles (AuNPs), multi-branched gold nanoparticles (MBGNs), and silica-coated MBGNs (MBGNs-silica) were studied for rhodamine B (RB) and alpha-glucose detection at low concentration. The MBGNs SPR band in the NIR, which is tunable, is useful for SERS that was demonstrated using rhodamine B and alpha-glucose as probe molecules with detection limits of 50 pM and 5 mM (90 mg dL(-1)), respectively, much lower than that using regular AuNPs. The SERS signals of RB and alpha-glucose using MBGNs-silica are further enhanced with respect to AuNPs and MBGNs, which is attributed to the aggregation of the MBGNs and a stronger interaction. In the case of alpha-glucose, the functionalization process performed to both, alpha-glucose molecules and MBGNs, improves the interaction and allows measurements at low concentration.
机译:研究了金纳米颗粒(AuNPs),多支金纳米颗粒(MBGNs)和二氧化硅包覆的MBGNs(MBGNs-二氧化硅)在低浓度下的若丹明B(RB)和α-葡萄糖检测。 NIR中的MBGNs SPR条带是可调节的,可用于SERS,使用罗丹明B和α-葡萄糖作为探针分子分别具有50 pM和5 mM(90 mg dL(-1))的检测限证明了这一点,与使用常规AuNP相比要低得多。相对于AuNPs和MBGNs,使用MBGNs-silica的RB和α-葡萄糖的SERS信号进一步增强,这归因于MBGNs的聚集和更强的相互作用。在使用α-葡萄糖的情况下,对α-葡萄糖分子和MBGN进行的功能化过程可改善相互作用,并允许在低浓度下进行测量。

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