首页> 外文期刊>RSC Advances >An efficient one-pot access to N-(pyridin-2-ylmethyl) substituent biphenyl-4-sulfonamides through water-promoted, palladium-catalyzed, microwave-assisted reactions
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An efficient one-pot access to N-(pyridin-2-ylmethyl) substituent biphenyl-4-sulfonamides through water-promoted, palladium-catalyzed, microwave-assisted reactions

机译:通过水促进的钯催化的微波辅助反应,有效地一锅获得N-(吡啶-2-基甲基)取代基联苯-4-磺酰胺

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摘要

An efficient one-pot, Pd(PPh3)(4) catalyzed, water-promoted method for the synthesis of N-(pyridin-2-ylmethyl) biphenyl-4-sulfonamides was developed under microwave irradiation. This methodology is acid free, has good substrate scope, excellent functional group compatibility, and excellent product yields, and is superior to the existing procedures for the synthesis of biphenyl-4-sulfonamides bearing a pyridin-2-ylmethyl group.
机译:在微波辐射下开发了一种高效的一锅法,Pd(PPh3)(4)催化,水促进的N-(吡啶-2-基甲基)联苯-4-磺酰胺合成方法。该方法是无酸的,具有良好的底物范围,优异的官能团相容性和优异的产物收率,并且优于合成具有吡啶-2-基甲基的联苯-4-磺酰胺的现有方法。

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