Efficacy of anakinra treatment in a patient with colchicine-resistant familial Mediterranean fever

AlpayN.; ?umnuA.; ?alI?kanY.; YazIcIH.; TürkmenA.; GülA.

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Efficacy of anakinra treatment in a patient with colchicine-resistant familial Mediterranean fever

机译：秋水仙碱治疗对耐秋水仙碱的家族性地中海热患者的疗效

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Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by self-limited recurrent attacks of fever and serositis. The serious complication of FMF is AA-type amyloidosis, which can result in end-stage renal disease. Although colchicine is effective in the majority of patients, there is no established treatment for those who are resistant or intolerant to colchicine. We herein report the efficacy of anakinra in a 52-year-old Turkish patient with FMF, secondary amyloidosis and renal transplant, who was resistant to colchicine treatment.

机译：家族性地中海热（FMF）是一种常染色体隐性遗传疾病，其特征是发烧和浆膜炎的自限性反复发作。 FMF的严重并发症是AA型淀粉样变性，可导致终末期肾脏疾病。尽管秋水仙碱对大多数患者有效，但尚无针对那些对秋水仙碱有抗性或不耐性的患者的治疗方法。我们在这里报告anakinra在FMM，继发性淀粉样变性和肾移植的52岁土耳其患者中的疗效，该患者对秋水仙碱治疗有抵抗力。

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《Rheumatology international.》 |2012年第10期|共3页
作者
AlpayN.; ?umnuA.; ?alI?kanY.; YazIcIH.; TürkmenA.; GülA.;
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正文语种 eng
中图分类免疫性疾病;
关键词
Amyloidosis; Anakinra; Familial Mediterranean fever; Renal transplantation;

机译：淀粉样变性;Anakinra;家族性地中海热;肾移植;

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1. Efficacy of anakinra treatment in a patient with colchicine-resistant familial Mediterranean fever [J] . AlpayN., ?umnuA., ?alI?kanY., Rheumatology international. . 2012,第10期

机译：秋水仙碱治疗对耐秋水仙碱的家族性地中海热患者的疗效
2. Effective treatment of a colchicine-resistant familial Mediterranean fever patient with anakinra. [J] . Kuijk LM, Govers AM, Frenkel J, Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2007,第11期

机译：有效的治疗秋水仙碱耐药的家族性地中海热患者的Anakinra。
3. The efficacy of anakinra in an adolescent with colchicine-resistant familial Mediterranean fever. [J] . Calligaris L, Marchetti F, Tommasini A, European journal of pediatrics . 2008,第6期

机译：Anakinra在青少年中对秋水仙碱耐药的家族性地中海热的疗效。
4. LACK OF CORRELATION BETWEEN AMYLOID A PROTEIN LEVELS AND CLINICAL PARAMETERS IN ASPIRATED FAT TISSUE OF FAMILIAL MEDITERRANEAN FEVER PATIENTS WITH SECONDARY AMYLOIDOSIS [C] . M Lidar, B P. Hazenberg, J Bijzet, International Symposium on Amyloidosis . 2008

机译：淀粉样蛋白蛋白质水平与家族地中海发热患者的吸气脂肪组织蛋白水平与临床参数之间的相关性
5. Defining the function of Pyrin, the Familial Mediterranean Fever-associated protein, in inflammation. [D] . Hesker, Pamela Rose. 2012

机译：定义了Pyrin（家族性地中海热相关蛋白）在炎症中的功能。
6. Colchicine-resistant familial Mediterranean fever in a renal transplantation patient: successful treatment with anakinra [O] . Zeynep Kendi Celebi, Orhan Kucuksahin, Sule Sengul, 2014

机译：肾移植患者耐秋水仙碱的家族性地中海热：anakinra成功治疗
7. Effective treatment of a colchicine-resistant familial Mediterranean fever patient with anakinra [O] . Kuijk, Loes M., Govers, Anita M. A. P., Hofhuis, Willem J. D., 2007

机译：带有秋水仙碱的秋水仙碱耐药家族性地中海热患者的有效治疗

Efficacy of anakinra treatment in a patient with colchicine-resistant familial Mediterranean fever

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