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首页> 外文期刊>Occupational and environmental medicine >Inhalable beta(1->3)glucans as a non-allergenic exposure factor in Dutch bakeries.
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Inhalable beta(1->3)glucans as a non-allergenic exposure factor in Dutch bakeries.

机译：可吸入的β（1-> 3）葡聚糖是荷兰面包店中的一种非过敏性暴露因子。

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OBJECTIVES: To obtain an overview of inhalable beta(1-->3)glucans levels in Dutch industrial bakeries and explore possible associations with reported respiratory health effects in bakery workers. METHODS: beta(1-->3)glucan levels were analysed in 186 personal inhalable dust measurements obtained from a random population of bakery workers. Association between respiratory health effects and exposure to beta(1-->3)glucan was explored in a population of industrial bakery workers participating in a Health Surveillance System for flour processing sectors. Based on their job, bakery workers were assigned to low or high exposure categories given the average job exposure estimates obtained from the measurement study. RESULTS: Bread bakers and dough makers had the highest exposures to beta(1-->3)glucans (GM 1.48 mug/m3 and 1.37 mug/m3 respectively). Strong correlations were found between airborne levels of inhalable dust and beta(1-->3)glucans, and between beta(1-->3)glucans and wheat allergens (Pearson correlation coefficients were 0.74 and 0.68 respectively). No significant associations could be identified between beta(1-->3)glucan exposure and work-related respiratory symptoms. CONCLUSION: This study has shown that bakery workers are exposed to inhalable beta(1-->3)glucan levels comparable with exposure levels found in other occupational settings. More refined exposure assessment is necessary to fully understand the role of beta(1-->3)glucan exposure on respiratory health in bakery workers.
机译：目的：概述荷兰工业面包房中可吸入的β（1-> 3）葡聚糖水平，并探讨其与面包店工人呼吸道健康影响的可能关联。方法：从随机的面包店工人中获得的186个个人可吸入粉尘测量值中分析了β（1-> 3）葡聚糖的含量。在参与面粉加工行业健康监控系统的工业面包店工人中，探索了呼吸健康影响与暴露于β（1-> 3）葡聚糖之间的关联。根据他们的工作，根据测量研究得出的平均工作暴露估计值，将面包店工人分配为低暴露或高暴露类别。结果：面包师和面团制造商对β（1-> 3）葡聚糖的暴露量最高（分别为GM 1.48杯/立方米和1.37杯/立方米）。发现空气中可吸入粉尘和β（1-> 3）葡聚糖的空气含量之间以及β（1-> 3）葡聚糖和小麦过敏原之间的相关性很强（Pearson相关系数分别为0.74和0.68）。没有发现β（1-> 3）葡聚糖暴露与工作相关的呼吸道症状之间有显着相关性。结论：这项研究表明，面包店工人暴露于可吸入的β（1-> 3）葡聚糖水平与其他职业环境中的暴露水平相当。为了全面了解β（1-> 3）葡聚糖暴露对面包店工人呼吸系统健康的作用，必须进行更精细的暴露评估。

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