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Relationship between outdoor temperature and blood pressure.

机译:室外温度与血压之间的关系。

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OBJECTIVES: Cardiovascular mortality has been linked to changes in outdoor temperature. However, the mechanisms behind these effects are not well established. We aimed to study the effect of outdoor temperature on blood pressure, as increased blood pressure is a risk factor for cardiovascular death. METHODS: The study population consisted of men aged 53-100 years living in the Boston area. We used a mixed effects model to estimate the effect of three temperature variables: ambient, apparent and dew point temperature (DPT), on repeated measures (every 3-5 years) of diastolic (DBP) and systolic blood pressure (SBP). Random intercepts for subjects and several possible confounders were used in the models, including black carbon and barometric pressure. RESULTS: We found modest associations between DBP and ambient and apparent temperature. In the basic models, DBP in association with a 5 degrees C decrease in 7-day moving averages of temperatures increased by 1.01% (95% CI -0.06% to 2.09%) and 1.55% (95% CI 0.61% to 2.49%) for ambient and apparent temperature, respectively. Excluding extreme temperatures strengthened these associations (2.13%, 95% CI 0.66% to 3.63%, and 1.65%, 95% CI 0.41% to 2.90%, for ambient and apparent temperature, respectively). Effect estimates for DPT were close to null. The effect of apparent temperature on SBP was similar (1.30% increase (95% CI 0.32% to 2.29%) for a 5 degrees C decrease in 7-day moving average). CONCLUSIONS: Cumulative exposure to decreasing ambient and apparent temperature may increase blood pressure. These findings suggest that an increase in blood pressure could be a mechanism behind cold-related, but not heat-related, cardiovascular mortality.
机译:目的:心血管死亡率与室外温度的变化有关。但是,这些作用背后的机制尚未完全确立。我们旨在研究室外温度对血压的影响,因为血压升高是心血管死亡的危险因素。方法:研究人群包括居住在波士顿地区的53至100岁的男性。我们使用混合效应模型来评估三个温度变量(环境温度,表观温度和露点温度(DPT))对舒张压(DBP)和收缩压(SBP)的重复测量(每3-5年)的影响。在模型中使用受试者的随机截距和几种可能的混杂因素,包括黑碳和大气压力。结果:我们发现DBP与环境温度和表观温度之间存在适度的关联。在基本模型中,与7天移动平均温度降低5摄氏度相关的DBP分别提高了1.01%(95%CI -0.06%至2.09%)和1.55%(95%CI 0.61%至2.49%)分别用于环境温度和表观温度。排除极端温度会增强这些关联性(环境温度和表观温度分别为2.13%,95%CI 0.66%至3.63%和1.65%,95%CI 0.41%至2.90%)。 DPT的效果估计接近零。表观温度对SBP的影响是相似的(7天移动平均值下降5摄氏度时,升高1.30%(95%CI为0.32%至2.29%))。结论:累积暴露于降低的环境温度和表观温度可能会增加血压。这些发现表明,血压升高可能是与冷相关但与热无关的心血管死亡率背后的机制。

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