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首页> 外文期刊>Occupational and environmental medicine >Excess of mesotheliomas after exposure to chrysotile in Balangero, Italy.
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Excess of mesotheliomas after exposure to chrysotile in Balangero, Italy.

机译：意大利Balangero接触温石棉后，间皮瘤过多。

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BACKGROUND: Chrysotile from the mine in Balangero, Italy is considered to be free of tremolite. In a cohort study of miners and millers only two pleural cancers were reported, a finding considered to indicate that chrysotile has a low potency for inducing mesothelioma. However, follow-up ended in 1987 and white-collar workers and the employees of subcontractors were not studied. METHODS: To complete the case ascertainment, the study searched the Registry of Malignant Mesotheliomas of Piedmont for records of cases of pleural mesothelioma among the following: mine employees; employees of subcontractors or of other firms transporting or refining Balangero asbestos, asbestos ore or mine tailings; individuals exposed to air pollution from the mine or living with mine employees; and individuals exposed to mine tailings from Balangero. RESULTS: The study identified four new cases of pleural mesothelioma among blue-collar workers in the mine, in addition to the two reported in the cohort study. Thus, six mesotheliomas occurred, compared to the 1.5 expected (p<0.01). The study also identified three mesothelioma cases among white-collar employees at the mine, five in workers in the mine hired by subcontracting firms, and three among workers processing Balangero chrysotile outside the mine. Finally, 10 additional cases due to non-occupational exposure or exposure to re-used mine tailings were identified. CONCLUSIONS: The cluster of 14 mesothelioma cases among workers who were active in the mine and 13 among other people exposed to Balangero chrysotile provides further evidence that tremolite-free chrysotile is carcinogenic.
机译：背景：来自意大利Balangero矿山的温石棉被认为不含透闪石。在矿工和磨工的队列研究中，仅报道了两种胸膜癌，这一发现被认为表明温石棉诱导间皮瘤的效力较低。但是，后续行动于1987年结束，对白领工人和分包商的雇员没有进行研究。方法：为确定病例，该研究在皮埃蒙特恶性间皮瘤登记处搜索以下患者的胸膜间皮瘤病例记录：分包商或其他运输或精炼Balangero石棉，石棉矿石或矿山尾矿的公司的员工;受到矿山空气污染或与矿山雇员同住的个人;以及暴露于Balangero的矿山尾矿的个人。结果：除队列研究中报告的两例外，该研究还确定了该矿蓝领工人中的四例胸膜间皮瘤新病例。因此，与预期的1.5相比，发生了六次间皮瘤（p <0.01）。该研究还确定了矿山白领员工中的三例间皮瘤病例，分包公司雇用的矿山工人中的五例，矿山外处理Balangero温石棉的工人中的三例。最后，确定了另外10例非职业性暴露或重复利用的矿山尾矿暴露。结论：在矿井中活跃的工人中有14例间皮瘤病例，在暴露于Balangero温石棉中的其他人中有13例提供了进一步的证据，证明不含透闪石的温石棉具有致癌性。

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