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首页> 外文期刊>Occupational and environmental medicine >Cross-shift and longitudinal changes in FEV1 among wood dust exposed workers
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Cross-shift and longitudinal changes in FEV1 among wood dust exposed workers

机译：木粉尘暴露工人中FEV1的交叉移位和纵向变化

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Objectives: Acute lung function (LF) changes might predict an accelerated decline in LF. In this study, we investigated the association between cross-shift and longitudinal changes in forced expiratory volume in 1 s (FEV1) among woodworkers in a 6-year follow-up study. Methods: 817 woodworkers and 136 controls participated with cross-shift changes of FEV 1 at baseline and FEV1 and forced vital capacity at follow-up. Height and weight were measured and questionnaire information on respiratory symptoms, employment and smoking habits was collected. Wood dust exposure was assessed from 3572 personal dust measurements at baseline and follow-up. Cumulative wood dust exposure was assessed by a study-specific job exposure matrix and exposure time. Results: The median (range) of inhalable dust at baseline and cumulative wood dust exposure was 1.0 (0.2-9.8) mg/m 3 and 3.8 (0-7.1) mg year/m3, respectively. Mean (SD) for %ΔFEV1/workday and ΔFEV1/year was 0.2 (6.0)%, and -29.1 (41.8) ml. Linear regression models adjusting for smoking, age, height and weight change showed no association between cross-shift and annual change in FEV1 among woodworkers or controls. Including different exposure estimates, atopy or cross-shift change dichotomised or as quartiles did not change the results. Conclusions: This study among workers exposed to low levels of wood dust does not support an association between acute LF changes and accelerated LF decline.
机译：目的：急性肺功能（LF）的改变可能预示着LF的加速下降。在这项研究中，我们对木工进行了为期6年的随访研究，研究了横向移位与强迫呼吸量在1 s（FEV1）的纵向变化之间的关联。方法：817名木工和136名对照参加了基线时FEV 1和FEV1的交叉移位变化以及随访时的强制肺活量。测量身高和体重，并收集有关呼吸道症状，就业和吸烟习惯的问卷信息。在基线和随访期间，根据3572个人的粉尘测量值评估了木屑的暴露量。通过研究特定的工作暴露矩阵和暴露时间评估累积的木屑暴露量。结果：可吸入粉尘在基线和累积木屑暴露量的中位数（范围）分别为1.0（0.2-9.8）mg / m 3和3.8（0-7.1）mg年/ m3。 ％ΔFEV1/工作日和ΔFEV1/年的平均值（SD）为0.2（6.0）％和-29.1（41.8）ml。调整了吸烟，年龄，身高和体重变化的线性回归模型显示，木工或对照组的FEV1的交叉移位和年度变化之间没有关联。包括不同的暴露估计值，将特应性或交叉移位改变二等分或因为四分位数没有改变结果。结论：这项针对低木屑含量工人的研究不支持急性低频变化与加速低频下降之间的关联。

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