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首页> 外文期刊>Occupational and environmental medicine >Neuropsychiatric symptoms in past users of sheep dip and other pesticides.
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Neuropsychiatric symptoms in past users of sheep dip and other pesticides.

机译：过去使用绵羊油和其他杀虫剂的人的神经精神症状。

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OBJECTIVES: To explore the prevalence and pattern of neuropsychiatric symptoms in past users of sheep dip and other pesticides. METHODS: From a postal survey of men born between 1933 and 1977 and resident in three rural areas of England and Wales (response rate 31%), data were obtained on lifetime history of work with pesticides, neurological symptoms in the past month, current mental health and tendency to be troubled by non-neurological somatic symptoms (summarised as a somatising tendency score). Risk factors for current neuropsychiatric symptoms were assessed by modified Cox regression. RESULTS: Data were available for 9844 men, including 1913 who had worked with sheep dip, 832 with other insecticides but not sheep dip and 990 with other pesticides but never with sheep dip or insecticides. Neurological symptoms were consistently 20-60% more common in past users of sheep dip than in men who had never worked with pesticides, but their prevalence was also higher in men who had worked only with pesticides other than sheep dip or insecticides. They clustered strongly within individuals, but this clustering was not specific to men who had worked with sheep dip. Reporting of three or more neurological symptoms was associated with somatising tendency (prevalence ratio (PR) 15.0, 95% CI 11.4 to 19.5, for the highest vs the lowest category of somatisation) and was more common in users of sheep dip (PR 1.3, 95% CI 1.0 to 1.6), other insecticides (PR 1.4, 95% CI 1.0 to 1.8) and other pesticides (PR 1.3, 95% CI 1.0 to 1.7) than in non-users. Among users of sheep dip, prevalence was higher in men who had dipped most often, but not in those who had worked with sheep dip concentrate. Past use of pesticides was not associated with current anxiety or depression. CONCLUSION: Neurological symptoms are more common in men who have worked with sheep dip, but the association is not specific to sheep dip or insecticides. A toxic cause for the excess cannot be ruled out, but several features of our observations suggest that psychological mechanisms have a role.
机译：目的：探讨过绵羊浸膏和其他农药使用者的神经精神症状的患病情况和模式。方法：通过对1933年至1977年之间出生并居住在英格兰和威尔士三个农村地区的男性进行的邮政调查（答复率为31％），获得了有关农药工作生涯史，过去一个月的神经系统症状，当前精神状况的数据。健康和容易受非神经性躯体症状困扰的趋势（概括为躯体化趋势评分）。通过改进的Cox回归评估当前神经精神症状的危险因素。结果：可获得9844名男性的数据，其中包括1913年使用绵羊浸剂工作的人，832使用其他杀虫剂但不使用绵羊浸剂的工作人员和990使用其他杀虫剂但从未使用绵羊浸剂或杀虫剂工作的人。与过去从未使用过杀虫剂的男性相比，过去曾使用过绵羊浸剂的人的神经系统症状持续普遍多出20-60％，但是在只使用除绵羊油或杀虫剂以外的其他农药的男性中，其神经病患病率也更高。他们在个人中强烈地聚集在一起，但是这种聚集并不是专门针对那些浸过羊的人的。三种或三种以上神经系统症状的报告与躯体化趋势相关（躯体化的最高比率与最低比率，患病率（PR）为15.0，95％CI为11.4至19.5），并且在绵羊浸肉使用者中更为常见（PR 1.3， 95％CI 1.0至1.6），其他杀虫剂（PR 1.4、95％CI 1.0至1.8）和其他农药（PR 1.3、95％CI 1.0至1.7）。在使用绵羊油浸膏的人群中，最经常浸膏的男性患病率较高，但在使用绵羊油浸膏工作的男性中患病率较高。过去使用农药与当前的焦虑或抑郁无关。结论：神经系统症状在绵羊皮浸染的男性中更为普遍，但这种关联并不特定于绵羊皮浸染剂或杀虫剂。不能排除造成过量的有毒原因，但是我们观察的一些特征表明心理机制起作用。

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