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首页> 外文期刊>Occupational and environmental medicine >Organochlorine in the serum of inhabitants living near an electrochemical factory.
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Organochlorine in the serum of inhabitants living near an electrochemical factory.

机译：住在电化学工厂附近居民的血清中的有机氯。

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摘要

OBJECTIVES: To measure the impact of occupational and lifestyle factors on concentrations of organochlorine compounds in a general population sample living near an electrochemical factory with a high airborne concentration of hexachlorobenzene (HCB). METHODS: Serum samples from 608 people (328 selected from a random sample) were collected in 1994. Information on lifestyles, occupation, and medical condition was obtained by questionnaire. RESULTS: HCB and polychlorinated biphenyls (PCBs) were detected in all samples (means 36.7 ng/ml and 4.3 ng/ml respectively), followed by dichlorodiphenyl dichloroethane (DDE) and beta-hexachlorocyclohexane (beta-HCH), found in 98.7% and 87.3% of the samples respectively (means 4.6 ng/ml and 2.5 ng/ml, respectively). Concentrations of HCB were the highest ever reported. Occupation in the factory was the main determinant of the variation in concentrations of HCB (regression coefficients 1.52 (SEM 0.14) in 1n (HCB) for workers in the production department, and 2.13 (0.23) for workers in maintenance department) and explained the highest concentrations of HCB found in men of middle age. In retired workers, concentrations of HCB declined with time since retirement. The PCBs, dichlorodiphenyl trichloroethane (DDT), and beta-HCH were independent of the occupation and concentrations were similar to those found in other populations. Concentrations of beta-HCH and DDE in the whole population, and HCB among non-workers, were higher in women than in men. Concentrations of all measured organochlorine compounds increased with age and body mass index. Consumption of locally caught fish was an independent determinant of HCB and PCB concentrations. CONCLUSIONS: This population incorporated HCB directly through occupation in the electrochemical factory, by airborne pollution, and consumption of locally caught fish. Concentrations of other common organochlorine compounds were not higher than expected. Environmental exposures to these compounds deserve attention due to their persistence and potential health effects.
机译：目的：测量职业和生活方式因素对生活在空气中六氯苯（HCB）浓度高的电化学工厂附近的一般人群样本中有机氯化合物浓度的影响。方法：1994年收集了608人的血清样本（从随机样本中选择328例）。通过问卷调查获得有关生活方式，职业和医疗状况的信息。结果：所有样品中均检测到六氯代苯和多氯联苯（分别为36.7 ng / ml和4.3 ng / ml），其次是二氯二苯基二氯乙烷（DDE）和β-六氯环己烷（β-HCH），检出率为98.7％，分别为87.3％的样品（分别为4.6 ng / ml和2.5 ng / ml）。六氯代苯的浓度是有史以来最高的。工厂中的职业是HCB浓度变化的主要决定因素（生产部门工人1n（HCB）的回归系数为1.52（SEM 0.14）在1n（HCB），维护部门工人为2.13（0.23））。在中年男性中发现六氯苯的浓度自退休以来，退休工人中六氯代苯的浓度随时间下降。多氯联苯，二氯二苯基三氯乙烷（DDT）和乙型六氯环己烷与职业无关，其浓度与其他人群中的相似。妇女的总体乙型六氯环己烷和六溴二苯醚的浓度以及非劳动者中的六氯代苯的浓度均高于男性。所有测得的有机氯化合物的浓度均随着年龄和体重指数的增加而增加。本地捕捞鱼的消费量是六氯代苯和多氯联苯浓度的独立决定因素。结论：该人群通过在电化学工厂中的职业，空气传播的污染以及当地捕捞的鱼类的消费直接将六氯代苯纳入其中。其他常见的有机氯化合物的浓度不高于预期。这些化合物的持久性和对健康的潜在影响，使其在环境中的暴露值得关注。

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