...
首页> 外文期刊>Occupational and environmental medicine >Air pollution from livestock farms, and asthma, allergic rhinitis and COPD among neighbouring residents
【24h】

Air pollution from livestock farms, and asthma, allergic rhinitis and COPD among neighbouring residents

机译:牧场居民的空气污染,以及邻近居民的哮喘,过敏性鼻炎和COPD

获取原文
获取原文并翻译 | 示例
           

摘要

Objectives: There is an ongoing debate regarding environmental health risks of exposures to dust and microbial agents from livestock farming in the Netherlands. The aims of the study were (1) to investigate associations between indicators of air pollution from livestock farms and asthma, allergic rhinitis and chronic obstructive pulmonary disease (COPD) among neighbouring residents; and (2) to assess associations between farm exposures and endotoxin levels in participants' homes. Methods: Electronic medical records of all 92 548 patients of 27 general practices in a rural area with a high density of animal farms were analysed, followed up by a case-control component using a subsample of the full population. Distance between livestock farms and home address, presence of livestock within 500 m, and particulate matter (PM)10 emissions from farms within 500 m were computed as proxies for farm exposure. Potential confounding was investigated through a case-control questionnaire study in 269 adult patients with asthma and 546 controls. Endotoxin levels were assessed in 493 homes. Results: Modelled PM10 emission was inversely associated with asthma, allergic rhinitis and COPD ( p<0.05). A smaller distance to the nearest farm, and the presence of swine, goat and sheep farms were also inversely related to respiratory morbidity, whereas mink farms showed positive associations with asthma and allergic rhinitis. Adjustment for confounding in the case-control study did not change results. Farm exposures were not associated with endotoxin levels in neighbouring residents' homes. Conclusions: In conclusion, indicators of air pollution from livestock farms were inversely associated with respiratory morbidity among neighbouring residents.
机译:目标:在荷兰,关于畜牧业接触粉尘和微生物制剂的环境健康风险正在进行辩论。该研究的目的是(1)调查附近居民的农场空气污染指标与哮喘,过敏性鼻炎和慢性阻塞性肺疾病(COPD)之间的关联; (2)评估参与者的家中农场暴露与内毒素水平之间的关联。方法:分析了农村地区高动物饲养场中27种常规做法的所有92 548名患者的电子病历,然后使用全部人群的子样本进行病例对照。牧场与家庭住址之间的距离,500 m以内的牲畜的存在以及500 m以内的农场的颗粒物(PM)10排放被计算为暴露于农场的代理。通过病例对照调查表调查了269名成年哮喘患者和546名对照患者的潜在混淆。评估了493个家庭的内毒素水平。结果:模拟的PM10排放与哮喘,过敏性鼻炎和COPD呈负相关(p <0.05)。距最近农场的距离更短,猪场,山羊场和绵羊场的存在也与呼吸系统发病率呈负相关,而水貂场则与哮喘和过敏性鼻炎呈正相关。病例对照研究中混杂因素的调整并没有改变结果。农场暴露与附近居民住宅中的内毒素水平无关。结论:总之,畜牧场空气污染指标与邻近居民的呼吸系统发病率呈负相关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号