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首页> 外文期刊>Occupational and environmental medicine >Non-Hodgkin's lymphoma among electric utility workers in Ontario: the evaluation of alternate indices of exposure to 60 Hz electric and magnetic fields.
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Non-Hodgkin's lymphoma among electric utility workers in Ontario: the evaluation of alternate indices of exposure to 60 Hz electric and magnetic fields.

机译：安大略省电力公司工作人员中的非霍奇金淋巴瘤：对暴露于60 Hz电场和磁场的其他指标的评估。

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OBJECTIVES: To examine associations between non-Hodgkin's lymphoma (NHL) and exposures to 60 Hz magnetic and electric fields in electric utility workers with a series of indices that capture a variety of aspects of field strength. METHODS: The study population consisted of 51 cases of NHL and 203 individually matched controls identified from within a cohort of male electric utility workers in Ontario. Odds ratios were calculated for several exposure indices with conditional logistic regression models. Aspects of exposure to electric and magnetic fields that were modelled included: the percentage of time spent above selected threshold field intensities, mean transitions in field strength, SD, and the arithmetic and geometric mean field intensities. RESULTS: For the most part, there was a lack of an association between exposure indices of magnetic fields and the incidence of NHL. Subjects in the upper tertile of percentage of time spent above electric field intensities of 10 and 40 V/m had odds ratios of 3.05 (95% confidence interval (95% CI) 1. 07 to 8.80) and 3.57 (1.30 to 9.80), respectively, when compared with those in the lowest tertile. Moreover, the percentages of time spent above these electric field thresholds were significant predictors of case status over and above the association explained by duration of employment and the arithmetic or geometric mean exposure. CONCLUSIONS: These data suggest that exposures above electric field threshold intensities of 10 and 40 V/m are important predictors of NHL. Consequently, the findings support the hypothesis that electric fields may play a promoting part in the aetiology of this cancer. Further occupational studies that include assessment of exposure to electric fields and measures of field strength above similar threshold cut off points are needed to confirm these findings.
机译：目的：研究非霍奇金淋巴瘤（NHL）与电力公司工人暴露于60 Hz磁场和电场之间的关联，并通过一系列指标来反映磁场强度的各个方面。方法：研究人群包括51例NHL病例和203例单独匹配的对照组，这些对照组是在安大略省的男性电力公司工人队列中确定的。使用条件逻辑回归模型计算了几种暴露指数的赔率。建模的暴露于电场和磁场的方面包括：在选定的阈值场强以上所花费的时间百分比，场强的平均跃迁，SD以及算术和几何平均场强。结果：在大多数情况下，磁场的暴露指数与NHL的发生率之间缺乏关联。电场强度高于10和40 V / m的时间所占时间百分比的上三分位数中的受试者的优势比为3.05（95％置信区间（95％CI）1. 07至8.80）和3.57（1.30至9.80），与最低三分位数相比。而且，花费在这些电场阈值之上的时间百分比是病例状态的重要预测指标，可以通过雇用时间以及算术或几何平均暴露来解释病例状况。结论：这些数据表明高于电场阈值强度10和40 V / m的暴露是NHL的重要预测指标。因此，这些发现支持以下假设：电场可能在这种癌症的病因中起促进作用。需要进一步的职业研究，包括评估暴露于电场的强度以及在类似阈值截止点以上的场强测量，以确认这些发现。

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