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首页> 外文期刊>Occupational and environmental medicine >Risk of enzyme allergy in the detergent industry.
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Risk of enzyme allergy in the detergent industry.

机译：洗涤剂行业中酶过敏的风险。

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摘要

OBJECTIVES: To assess the prevalence of enzyme sensitisation in the detergent industry. METHODS: A cross sectional study was conducted in a detergent factory. Sensitisation to enzymes was examined by skin prick and radioallergosorbent (RAST) tests. 76 Workers were tested; 40 in manufacturing, packing, and maintenance, and 36 non-exposed people in management and sales departments. The workers were interviewed for work related respiratory and skin symptoms. Total dust concentrations were measured by a gravimetric method, and the concentration of protease in air by a catalytic method. RESULTS: Nine workers (22%) were sensitised to enzymes in the exposed group of 40, whereas none were sensitised in the non-exposed group. All the sensitised people had symptoms at work; all had rhinitis and one had asthma. Protease concentrations were generally < 20 ng/m3, but occasional peak values up to 80 ng/m3 were detected in the packing and maintenance tasks, and high values of > 1 microgram/m3 in the mixing area. CONCLUSION: Despite the use of encapsulated enzyme preparations, high enzyme concentrations in workplace air are possible, resulting in a higher risk of sensitisation than expected.
机译：目的：评估洗涤剂行业中酶敏化的发生率。方法：在洗涤剂厂进行了横截面研究。通过皮肤点刺和放射性过敏吸附（RAST）测试检查对酶的敏感性。测试了76名工人;制造，包装和维护部门有40名，管理和销售部门有36名非接触人员。工人接受了与工作有关的呼吸道和皮肤症状的采访。通过重量分析法测量总粉尘浓度，通过催化方法测量空气中蛋白酶的浓度。结果：40名暴露组中有9名工人（22％）对酶敏感，而未暴露组中没有人对酶致敏。所有的敏感人群在工作中都有症状。所有人都患有鼻炎，其中之一患有哮喘。蛋白酶浓度通常<20 ng / m3，但在包装和维护任务中偶尔会发现高达80 ng / m3的峰值，而在混合区域中检测到的峰值最高> 1微克/ m3。结论：尽管使用了胶囊化酶制剂，但工作场所空气中的高浓度酶还是有可能的，导致致敏的风险比预期的高。

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