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首页> 外文期刊>Occupational and environmental medicine >Exposure assessment of monoterpenes and styrene: a comparison of air sampling and biomonitoring.
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Exposure assessment of monoterpenes and styrene: a comparison of air sampling and biomonitoring.

机译：单萜和苯乙烯的暴露评估：空气采样和生物监测的比较。

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BACKGROUND: Within- and between-worker variance components have seldom been reported for both environmental and biological data collected from the same persons. AIMS: To estimate these variance components and their ratio for air contaminants and urinary metabolites in two different work environments and to predict the attenuation of exposure-response relationships based on these measures. METHODS: Parallel measurements of air and urine were performed among workers exposed to monoterpenes in sawmills (urinary metabolite: verbenol) and styrene in reinforced plastics factories (urinary metabolite: mandelic acid). RESULTS: Among the sawmill workers, variance components of the air and urinary verbenol results were similar; for the reinforced plastics workers the estimated between-worker variance component was greater for styrene in air than mandelic acid in urine. This suggests that attenuation bias would be about equal if air or biological monitoring were employed for monoterpene exposures, but would be greater if urinary mandelic acid were used instead of airborne styrene in an investigation of styrene exposure. CONCLUSIONS: Personal air samplers provide data with similar or superior quality to urinary metabolites as measures of exposure to these monoterpenes in sawmills and styrene in reinforced plastics factories.
机译：背景：很少有关于从同一人收集的环境和生物学数据的工人内部和工人之间差异的报告。目的：在两个不同的工作环境中，估算这些差异分量及其对空气污染物和尿液代谢产物的比率，并根据这些度量预测暴露-反应关系的衰减。方法：平行测量空气和尿液的工人是在锯木厂暴露于单萜的工人（尿代谢物：马鞭草酚）和增强塑料工厂中的苯乙烯（尿代谢物：扁桃酸）。结果：在锯木厂工人中，空气和尿中马鞭草的结果的方差相似。对于增强塑料工人，空气中苯乙烯的估计工人之间差异大于尿中的扁桃酸。这表明如果对单萜暴露进行空气或生物学监测，衰减偏差将大致相等，但是在研究苯乙烯暴露时，如果使用尿扁桃酸代替空气传播的苯乙烯，衰减偏差将更大。结论：个人空气采样器提供的数据与尿液代谢产物具有相似或更高的质量，以此作为测量锯木厂中这些单萜和塑料工厂中苯乙烯含量的指标。

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