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Biomonitoring of a worker population exposed to platinum dust in a catalyst production plant.

机译:在催化剂生产厂对暴露于铂尘的工人进行生物监控。

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AIMS: To evaluate the occupational exposure to platinum in an industrial plant engaged in the production, recovery, and recycling of catalytic converters for the automotive traction and chemical industries. METHODS: Pt was determined in airborne particulate matter, and blood, urine, and hair of 106 exposed workers, 21 controls from the plant's administrative offices, and 25 unexposed subjects. RESULTS: The highest air Pt level was found in the department of the plant in which supports are coated with acid metal solutions, where values of 2.39 and 4.83 microg/m3 respectively were found in environmental airborne particulate matter and in air collected using personal sampler devices. The percentage of soluble Pt was also highest in this area, varying from 24% to 44% of the total. The biological data confirmed this trend, with mean concentrations in this site being higher than in other working areas: 1.86 microg/l (urine), 0.38 microg/l (blood), and 2.26 microg/kg (hair). The workers employed in the administrative sector, who were not directly exposed to Pt, had levels of contaminant lower than those of other workers, albeit 2-20 times higher than those of external controls. High correlations were obtained between Pt levels detected in airborne samples using personal devices and those found in urine and hair, but not in blood. CONCLUSIONS: The background level of Pt in all areas of the factory implies widespread exposure for the workers. The most reliable biomarker was urine. Hair cannot be considered a good index of time related exposure, at least until more reliable methods of washing can be found that are able to remove exogenous Pt completely.
机译:目的:评估一家从事汽车牵引和化学工业中催化转化器生产,回收和再循环的工厂中铂的职业暴露。方法:测定了106名暴露的工人,工厂行政办公室的21名控制人员和25名未暴露的受试者的空气中颗粒物,血液,尿液和头发中的Pt。结果:在工厂部门发现空气中的最高Pt含量是用酸性金属溶液涂覆的,在环境空气中的颗粒物和使用个人采样器收集的空气中分别发现了2.39和4.83 microg / m3的值。 。可溶性Pt的百分比在该地区也最高,占总量的24%至44%。生物学数据证实了这种趋势,该部位的平均浓度高于其他工作区域:1.86微克/升(尿液),0.38微克/升(血液)和2.26微克/千克(头发)。未直接接触Pt的行政部门工作人员的污染物水平低于其他工人,尽管比外部控制人员高2-20倍。使用个人设备在空气样本中检测到的Pt水平与在尿液和头发中检测到的Pt水平(但在血液中检测不到)之间具有高度相关性。结论:工厂所有区域的铂的背景水平意味着工人的广泛暴露。最可靠的生物标志物是尿液。至少在找到能够完全去除外源Pt的更可靠的洗涤方法之前,不能认为头发是与时间有关的暴露的良好指标。

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