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The joint association of air pollution and noise from road traffic with cardiovascular mortality in a cohort study

机译:在一项队列研究中,道路交通中的空气污染和噪声与心血管疾病死亡率的联合关联

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Objectives: Associations between cardiovascular mortality and air pollution and noise together were investigated.Methods: Data from the ongoing Netherlands Cohort Study on Diet and Cancer (120 852 subjects; follow-up 1987-1996) were used/Cox proportional hazard analyses were conducted for the association between cardiovascular mortality and exposure to black smoke, traffic intensity on the nearest road and road traffic noise at the home address.Results: The correlations between traffic noise and background black smoke, and traffic intensity on the nearest road were moderate at 0.24 and 0.30, respectively. Traffic intensity was associated with cardiovascular mortality, with highest relative risk (95% confidence interval) for ischaemic heart disease (IHD) mortality being 1.11 (1.03 to 1.20) (increment 10 000 motor vehicles/24 h). Relative risks for black smoke concentrations were elevated for cerebrovascular (1.39 (0.99 to 1.94)) and heart failure mortality (1.75 (1.00 to 3.05)) (increment 10 mug/m~3). These associations were insensitive to adjustment for traffic noise. There was an excess of cardiovascular mortality in the highest noise category (>65 dB(A)), with elevated risks for IHD (1.15 (0.86 to 1.53)) and heart failure mortality (1.99 (1.05 to 3.79)). After adjustment for black smoke and traffic intensity, noise risk reduced to unity for IHD mortality and was slightly reduced for heart failure mortality.
机译:目的:研究心血管疾病死亡率与空气污染和噪声之间的关联。方法:使用正在进行的荷兰饮食与癌症队列研究(120 852名受试者; 1987-1996年随访)的数据/进行了Cox比例风险分析结果:交通噪声与背景黑烟之间的相关性与最近道路上的交通强度之间的相关性为中等,为0.24,且与最近家道路上的交通噪声之间的相关性为中等。分别为0.30。交通强度与心血管疾病死亡率相关,缺血性心脏病(IHD)死亡率的最高相对风险(95%置信区间)为1.11(1.03至1.20)(每10小时增加1万辆汽车)。脑血管黑烟浓度的相对风险(1.39(0.99至1.94))和心力衰竭死亡率(1.75(1.00至3.05))(升高10杯/ m〜3)升高。这些关联对调整交通噪声不敏感。在最高噪声类别(> 65 dB(A))中,心血管疾病死亡率过高,IHD(1.15(0.86至1.53))和心力衰竭死亡率(1.99(1.05至3.79))的风险较高。在调整了黑烟和交通强度之后,噪声风险降低到IHD死亡率的统一水平,而心衰死亡率则略有降低。

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